Results 181 to 190 of about 525,389 (295)

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Abscisic acid enhances DNA damage response through the nuclear shuttling of clathrin light chain 2 in plant cells. [PDF]

open access: yesSci Adv
Jiang J   +15 more
europepmc   +1 more source

Whether do plant cells sense nitrate changes without a sensor? [PDF]

open access: yesFront Plant Sci, 2022
Fu YF   +4 more
europepmc   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Quantitative dissection of Agrobacterium T-DNA expression in single plant cells reveals density-dependent synergy and antagonism. [PDF]

open access: yesNat Plants
Alamos S   +12 more
europepmc   +1 more source

Genome-scale metabolic model led engineering of Nothapodytes nimmoniana plant cells for high camptothecin production. [PDF]

open access: yesFront Plant Sci, 2023
Murali S   +6 more
europepmc   +1 more source

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