Results 51 to 60 of about 2,510,143 (277)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The impact of drought on wheat leaf cuticle properties
Background The plant cuticle is the outermost layer covering aerial tissues and is composed of cutin and waxes. The cuticle plays an important role in protection from environmental stresses and glaucousness, the bluish-white colouration of plant surfaces
Huihui Bi +5 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
A Permeable Cuticle, Not Open Stomata, Is the Primary Source of Water Loss From Expanding Leaves
High rates of water loss in young, expanding leaves have previously been attributed to open stomata that only develop a capacity to close once exposed to low humidity and high abscisic acid (ABA) levels.
Cade N. Kane +3 more
doaj +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Fusion of Biotechnology and Craftsmanship: Bacterial Treatment to Improve Bashofu Fiber Extraction
Bashofu is a traditional Okinawan textile made from thin banana fibers. The raw materials derived from banana leaf sheaths are composed of plant fibers and unwanted constituents such as the plant cuticle layer.
Yoko Nomura, Koji Koizumi
doaj +1 more source
Plant Manipulation by Gall-Forming Social Aphids for Waste Management
Many social aphids form spectacular galls on their host plants, in which hundreds to thousands of aphids thrive for several months or even for over a year.
Mayako Kutsukake +2 more
doaj +1 more source
Background The plant cuticle represents one of the major adaptations of vascular plants to terrestrial life. Cuticular permeability and chemical composition differ among species.
Martina Vráblová +4 more
doaj +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Origins and Evolution of Cuticle Biosynthetic Machinery in Land Plants
Portions of the cuticle biosynthetic machinery originated in the last common ancestor of embryophytes and underwent evolution and diversification in land plants.
Xu, Bo +6 more
core +1 more source

