Results 91 to 100 of about 720,222 (280)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Trichoderma atroviride P1 Colonization of Tomato Plants Enhances Both Direct and Indirect Defense Barriers Against Insects [PDF]

, 2019
Numerous microbial root symbionts are known to induce different levels of enhanced plant protection against a variety of pathogens. However, more recent studies have demonstrated that beneficial microbes are able to induce plant systemic resistance that ...
CASCONE, PASQUALE, Coppola M, Di Lelio I, Digilio MC, Guerrieri E, Lorito M, Pennacchio F, Rao R, Woo SL   +8 more
core   +2 more sources

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Plant perception of β-aminobutyric acid is mediated by an aspartyl-tRNA synthetase [PDF]

, 2014
Specific chemicals can prime the plant immune system for augmented defense. β-aminobutyric acid (BABA) is a priming agent that provides broad-spectrum disease protection.
A Kohler, A Shrift, A Slaughter, AJ Lloyd, Allison van de Meene, AM Duchêne, Ana López, B Mauch-Mani, B Ulmasov, Beining Chen, BK Nelson, C-C Wu, CA Frye, CJ Bell, CMJ Pieterse, Corné M J Pieterse, D Silué, D Walters, DR Walters, E Luna, E Schmitt, EB Holub, Estrella Luna, G Wu, GJM Beckers, HW Jung, I Cestari, J Cavarelli, J Ton, J Ton, JE Parker, JJ Lin, Jurriaan Ton, K Audenaert, KW Earley, L Zimmerli, M Guo, M Guo, M Guo, M van Hulten, Marieke van Hulten, Matthew A Sellwood, Mike Burrell, MW Li, O Berkowitz, Oliver Berkowitz, P Pétriacq, P Singh, Pierre Pétriacq, Q Kong, S Ahmad, S Van der Ent, SJ Clough, T Czechowski, TE Dever, TP Delaney, U Conrath, U Conrath, V Flors, V Pastor, Victor Flors, Y Cohen, Y Cohen, Y Zhang, Y-G Ko, YR Cohen, Yuhua Zhang   +66 more
core   +6 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Role of Silicon on Plant–Pathogen Interactions

Frontiers in Plant Science, 2017
Although silicon (Si) is not recognized as an essential element for general higher plants, it has beneficial effects on the growth and production of a wide range of plant species.
Min Wang, Limin Gao, Suyue Dong, Yuming Sun, Qirong Shen, Shiwei Guo   +5 more
doaj   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Insights into the plant response to nematode invasion and modulation of host defense by plant parasitic nematode

Frontiers in Microbiology
Plant pathogens cause diseases by suppressing plant immune response and interacting with plant cells. Investigating these interactions assists in decoding the molecular strategies the pathogen uses to overcome plant immunity.
Xiaolong Chen, Fuqiang Li, Ding Wang, Liqun Cai   +3 more
doaj   +1 more source

Chitinases—Potential Candidates for Enhanced Plant Resistance towards Fungal Pathogens

Agriculture, 2018
Crop cultivation is crucial for the existence of human beings, as it fulfills our nutritional requirements. Crops and other plants are always at a high risk of being attacked by phytopathogens, especially pathogenic fungi.
Manish Kumar, Amandeep Brar, Monika Yadav, Aakash Chawade, V. Vivekanand, Nidhi Pareek   +5 more
doaj   +1 more source

Reactive oxygen species generated in chloroplasts contribute to tobacco leaf infection by the necrotrophic fungus Botrytis cinerea [PDF]

, 2017
Reactive oxygen species (ROS) play fundamental roles in plant responses to pathogen infection, including modulation of cell death processes and defense-related gene expression.
Bisaro, Fabiana, Carrillo, Nestor Jose, Krapp, Adriana del Rosario, Maiale, Santiago Javier, Pieckenstain, Fernando Luis, Rossi, Franco Rubén   +5 more
core   +1 more source