Results 61 to 70 of about 725,519 (305)

Development of fad7-1 single mutant Arabidopsis thaliana plants that are resistant to aphids [PDF]

, 2014
Aphids are a group of sap-feeding insects that attack most of the world’s crops. The loss of function of fatty acid desaturase7 (FAD7) in Solanum lycopersicum (tomato plant) induces aphid resistance that is dependent upon the accumulation of plant ...
Avila, Carlos A., Goggin, Fiona L., Padilla-Marcia, Carmen S., Vaughn, Kaleb L.   +3 more
core   +2 more sources

An effector of the Irish potato famine pathogen antagonizes a host autophagy cargo receptor [PDF]

, 2016
Plants use autophagy to safeguard against infectious diseases. However, how plant pathogens interfere with autophagy-related processes is unknown. Here, we show that PexRD54, an effector from the Irish potato famine pathogen Phytophthora infestans, binds
Altschul, Bassham, Baxt, Berrow, Birgisdottir, Boyle, Bozkurt, Bozkurt, Bozkurt, Caillaud, Chaparro-Garcia, Choy, Dagdas, Fisher, Geldner, Hanamata, He, Huang, Ivanov, Kalvari, Karimi, Kumar, Kwon, Lamb, Larkin, Lenz, Li, Lipka, Liu, Lv, Morgan, Mostowy, Oh, Patel, Petre, Randow, Randow, Saunders, Segonzac, Shintani, Song, Stolz, Svenning, Teh, Vanhee, Wang, Win, Yoshimoto, Zientara-Rytter   +48 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Integrated metabolomics, transcriptomic, and phytohormonal analyses to study the effects of water stress and foliar abscisic acid application in Thymus species using LC-MS/MS

Frontiers in Plant Science
Thyme species, including Thymus vulgaris, T. kotschyanus (drought-tolerant) and T. serpyllum (drought-sensitive), are valuable medicinal herbs. They are often grown in arid regions and are increasingly suffering from water stress due to climate change ...
Maryam Alipour, Maryam Alipour, Maryam Haghighi, Mehdi Rahimmalek, Michael Reichelt, Laure Martinelli, Karin Groten, Axel Mithöfer   +7 more
doaj   +1 more source

An evolutionarily young defense metabolite influences the root growth of plants via the ancient TOR signaling pathway

eLife, 2017
To optimize fitness a plant should monitor its metabolism to appropriately control growth and defense. Primary metabolism can be measured by the universally conserved TOR (Target of Rapamycin) pathway to balance growth and development with the available ...
Frederikke Gro Malinovsky, Marie-Louise F Thomsen, Sebastian J Nintemann, Lea Møller Jagd, Baptiste Bourgine, Meike Burow, Daniel J Kliebenstein   +6 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Lectins as Plant Defense Proteins [PDF]

Plant Physiology, 1995
Many plant species contain carbohydrate-binding proteins, which are commonly referred to as either lectins or agglutinins. Generally speaking, lectins are proteins that bind reversibly to specific monoor oligosaccharides. Since the initial discovery of a hemagglutinating factor in castor bean extracts by Stillmark in 1888, several hundred of these ...
W J, Peumans, E J, Van Damme
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Site-specific differences in the bilberry (Vaccinium myrtillus) phyllosphere microbiome across temperate and arctic locations

Journal of Plant Interactions
The phyllosphere microbiome plays a crucial role in plant adaptation to environmental conditions, yet little is known about its variation across climate extremes.
Apurbha Saha, Laura Jaakola, Axel Mithöfer, Clabe Wekesa   +3 more
doaj   +1 more source

Histochemical and cytochemical investigations of phenols in leaves of banana infected by the Mycosphaerella fijiensis [PDF]

, 2009
Several types of biotic and abiotic stimulations are known as potential activators of phenolic compounds production on plants with defense mechanisms.
Cavalcante, M., Escoute, Jacques, Nicole, Michel, Verdeil, Jean-Luc   +3 more
core