Results 41 to 50 of about 162,451 (217)

FASCINATING WORLD OF TROPHIC INTERACTIONS – WHY IT IS IMPORTANT TO STUDY IT [FASCINUJÍCÍ SVĚT POTRAVNÍCH VAZEB ANEB PROČ JE DŮLEŽITÉ JE STUDOVAT] [PDF]

open access: yesVědecké Práce Ovocnářské
The purpose of this article is to give a comprehensive overview of the fascinating world of food webs, where plants play a key role. To highlight the importance of studying this area, understanding the issues involved, and applying the knowledge gained ...
Tomáš Bílek   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Plant Defense Chemicals against Insect Pests

open access: yesAgronomy, 2020
Insect pests cause significant global agricultural damage and lead to major financial and environmental costs. Crops contain intrinsic defenses to protect themselves from such pests, including a wide array of specialized secondary metabolite-based ...
Jessica P. Yactayo-Chang   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Advances in the Involvement of Metals and Metalloids in Plant Defense Response to External Stress

open access: yesPlants
Plants, as sessile organisms, uptake nutrients from the soil. Throughout their whole life cycle, they confront various external biotic and abiotic threats, encompassing harmful element toxicity, pathogen infection, and herbivore attack, posing risks to ...
Lingxiao Zhang   +4 more
doaj   +1 more source

Carrageenans from red seaweeds as promoters of growth and elicitors of defense response in plants

open access: yesFrontiers in Marine Science, 2016
Plants incessantly encounter abiotic and biotic stresses that limit their growth and productivity. However, conversely, plant growth can also be induced by treatments with various abiotic and biotic elicitors.
Pushp Sheel Shukla   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Silicon Effects Depend upon Insect Herbivore Guild and Has Limited Influence on Gall-Inducing Insects of Bauhinia brevipes

open access: yesPlants
Silicon (Si) is a widely recognized element in plant defense, often enhancing resistance to herbivory by strengthening cell walls and deterring feeding by external herbivores.
Guilherme Ramos Demetrio   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy