Results 121 to 130 of about 635,909 (318)

Proteome–Transcriptome Discordance in Rice Under Drought Is Modulated by Post-Translational Modifications with Functional Consequences for Photosynthesis and Energy Metabolism

Plants
Transcriptome profiling has been widely used to dissect the molecular mechanisms underlying plant responses to environmental stresses, yet the extent to which RNA changes reflect functional protein levels remains unclear. Here, we performed an integrated
Zhiyu Guo, Xiaohao Yan, Jiansheng Liang
doaj   +1 more source

Effects of Different Irrigation Levels with Bio-stimulant Applications on Plant Growth in ‘Kabarla’ Strawberry Variety

, 2017
In this study, the effects of different irrigation levels with bio-stimulant applications on leaf area, crown diameter, number of crown, leaf number and plant width were investigated in a variety of Kabarla. The trail was implemented as a 4×2 factorial
kapur, burcak
core   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

A mutually antagonistic mechanism mediated by RNA m6A modification in plant-virus interactions

Nature Communications
RNA-based immunity plays a central role in host defense against pathogens, with both hosts and pathogens continually evolving antagonistic strategies in their ongoing arms race.
Jia-Hui Liu, Yujing Lin, Ying-Xin Li, Zhaobo Lang, Zhonghui Zhang, Cheng-Guo Duan   +5 more
doaj   +1 more source

Prediction of Bleeding via Simulation of Hydrodynamics in Centrifugal Partition Chromatography

Separations
Centrifugal Partition Chromatography (CPC) utilizes a two-phase liquid–liquid system as mobile and stationary phases. During operation, the latter continuously drains out of the rotor, despite it being in fact stationary, leading to decreasing separation
Felix Buthmann, Sophia Volpert, Jörg Koop, Gerhard Schembecker   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Optimizing Chromatographic Separation with Redosing: Effects on Separation Efficiency of a Model System in Centrifugal Partition Chromatography

Separations
This study investigates and optimizes chromatographic separation in a Centrifugal Partition Chromatograph. Therefore, a model system is separated in a single-disc rotor.
Felix Buthmann, Jan Hohlmann, Mareen Neuwald, Gerhard Schembecker   +3 more
doaj   +1 more source

Technoeconomic evaluation of trigeneraton plant: Gas turbine performance, absorption cooling and district heating [PDF]

, 2006
This PhD thesis is a demand led study taking into account changes in ambient conditions and power settings of a tri-generation power plant. Includes an evaluation tool for combined heat, cooling and power generation plant.
Polyzakis, Apostolos
core  

Mapping customer needs to engineering characteristics: an aerospace perspective for conceptual design

, 2014
Designing complex engineering systems, such as an aircraft or an aero-engine, is immensely challenging. Formal Systems Engineering (SE) practices are widely used in the aerospace industry throughout the overall design process to minimise the overall ...
Eres, M.H., Scanlan, James, Kossmann, M., Kossman, Mario, Bertoni, M., Eres, Murat Hakki, Eres, Murat, Bertoni, Marco, Scanlan, J.P.   +8 more
core   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source