Results 131 to 140 of about 635,909 (318)

Comparative single-nucleus RNA-seq analysis revealed localized and cell type-specific pathways governing root-microbiome interactions

open access: yesNature Communications
Roots can recognize and differentially respond to beneficial and pathogenic microbes, which are fundamental for maintaining root microbiome homeostasis, plasticity, and plant fitness.
Qiuhua Yang   +10 more
doaj   +1 more source

Study of post-combustion Carbon Dioxide capture for coal-fired plant through modelling and simulation

open access: yes, 2010
Fossil-fuel power plants are the largest single source of carbon dioxide (CO2) emissions. Post-combustion capture through monoethanolamine-based absorption is viewed as the most mature technology proposed for mitigating CO2 emissions from such power ...
Lawal, Adekola
core  

Importance of Design Conditions for Sizing Air-Conditioning Plant [PDF]

open access: yes, 2000
Design conditions based on the meteorological data collected at two weather stations located less than 10 km away from each other within Kuwait City are presented for dry-bulb temperature (DBT) and web-bulb temperature (WBT) prioritization.
Maheshwari, G. P.   +2 more
core  

Overall plant design specification Modular High Temperature Gas-cooled Reactor. Revision 9

open access: yes, 1990
Revision 9 of the ``Overall Plant Design Specification Modular High Temperature Gas-Cooled Reactor,`` DOE-HTGR-86004 (OPDS) has been completed and is hereby distributed for use by the HTGR Program team members.

core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Chemical Engineering Design Principles, Practice and Economics of Plant and Process Design

open access: yes, 2013
commercial design projects from diverse industries A rigorous pedagogy assists learning, with detailed worked examples, end of chapter exercises, plus supporting data and Excel spreadsheet calculations plus over 150 Patent References, for downloading ...
Towler, Gavin, Sinnott, R K.
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Home - About - Disclaimer - Privacy