Results 181 to 190 of about 721,006 (297)

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Proline and ROS: A Unified Mechanism in Plant Development and Stress Response? [PDF]

Plants (Basel)
Renzetti M, Funck D, Trovato M.
europepmc   +1 more source

Influences of Quantitative Difference in Water Supply of Soil on the Growth and the Development of Bast Fibres in Flax Plant

, 1936
Keijiro YOSHIDA
openalex   +2 more sources

Some mechanisms involved in the development of iron toxicity symptoms in the rice plant [PDF]

, 1966
Akira Tanaka, Robert H. Loe, S. A. Navasero   +2 more
openalex   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

A novel molecular switch in plant growth: how adenosine kinase activity modulates plant development and growth pathways. [PDF]

J Exp Bot
Watson KM.
europepmc   +1 more source

The wheat plant: its origin, culture, growth, development, composition, varieties, diseases, etc., etc

John H. Klippart
openalex   +2 more sources

THE HF-H$sub 2$-LEACH (HFRL) TREATMENT FOR RECOVERY OF URANIUM FROM RESIDUES. PART IV. PLANT SCALE DEVELOPMENT

, 1947
A.G. Blasewitz, G.H. Clewett
openalex   +2 more sources

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Dancing molecules: group A bZIPs and PEBPs at the heart of plant development and stress responses. [PDF]

J Exp Bot
Martignago D, da Silveira Falavigna V, Coupland G, Conti L.   +3 more
europepmc   +1 more source