Results 181 to 190 of about 19,871,495 (298)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

TRB proteins in moss reveal their evolutionarily conserved roles in plant development and telomere maintenance. [PDF]

Plant J
Kusová A, Holá M, Petrová IG, Rudolf J, Zachová D, Skalák J, Hejátko J, Klodová B, Přerovská T, Lyčka M, Sýkorová E, Bertrand YJK, Fajkus J, Honys D, Schrumpfová PP.   +14 more
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Functions of triacylglycerols during plant development and stress.

Current Opinion in Biotechnology, 2018
Yang Yang, C. Benning
semanticscholar   +1 more source

An unknown apocarotenoid signal alters plant development by modulating shoot and root apical meristem activities. [PDF]

Plant Physiol
Bradley JM.
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

The centromeric gene OsDCL plays essential roles in plant development and yield production in rice. [PDF]

Plant Physiol
Li X, Xue C, Guo R, Wang Z, Liu K, Shen M, Ye L, Chen J, You H, Miao J, Chen L, Bian W, Zhou Y, Gong Z.   +13 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

E3 Ubiquitin Ligases: Ubiquitous Actors in Plant Development and Abiotic Stress Responses.

Plant and Cell Physiology, 2017
K. Shu, Wenyu Yang
semanticscholar   +1 more source

Land plant-specific H3K27 methyltransferases ATXR5 and ATXR6 control plant development and stress responses. [PDF]

Genome Biol
Li X, Pan J, Liu Q, Zhang H, Li H, Jiang D.   +5 more
europepmc   +1 more source