Results 201 to 210 of about 3,150,546 (347)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Peptide Hormone-Mediated Regulation of Plant Development and Environmental Adaptability. [PDF]

Adv Sci (Weinh)
Li X, Zhu L, Wang H, Zhou X, Wang M, Li L, Liu F, Sun J, Xiao G.   +8 more
europepmc   +1 more source

Development of the detoxification method for zinc plant leach residues by removing heavy metals using coupled extraction-cementation (CEC) process [an abstract of dissertation and a summary of dissertation review]

, 2021
Marthias Silwamba
openalex   +1 more source

Analysis of accumulation and acute phytotoxic reactions of Ocimum basilicum to lead contamination in the initial phases of plant development

, 2023
Maria Godyaeva, Nadezhda I. Uyutova
openalex   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Enhancers in Plant Development, Adaptation and Evolution. [PDF]

Plant Cell Physiol
Beernink BM, Vogel JP, Lei L.
europepmc   +1 more source

The Development of E-Handout Teaching Materials for the Sub-Concept of Structure and Function of Tissues in Plants

, 2023
Anisa Rahmatina, Noorhidayati Noorhidayati, Aulia Ajizah   +2 more
openalex   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Regulatory roles of RNA modifications in plant development and fruit ripening. [PDF]

aBIOTECH
Li T, Huang J, Wang G, Li H, Lü P.
europepmc   +1 more source

Development of Progress Management System based on Quality Inspection Information - Case Study on Nuclear Power Plant Construction - [PDF]

, 2011
Kwahk Kil-Jong, Jae-Jun Kim
openalex   +1 more source