Results 121 to 130 of about 1,416,680 (355)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Status on Genetic Resistance to Rice Blast Disease in the Post-Genomic Era

Plants
Rice blast, caused by Magnaporthe oryzae, is a major threat to global rice production, necessitating the development of resistant cultivars through genetic improvement.
Rodrigo Pedrozo, Aron Osakina, Yixiao Huang, Camila Primieri Nicolli, Li Wang, Yulin Jia   +5 more
doaj   +1 more source

Exploration of Plant-Microbe Interactions for Sustainable Agriculture in CRISPR Era

Microorganisms, 2019
Plants and microbes are co-evolved and interact with each other in nature. Plant-associated microbes, often referred to as plant microbiota, are an integral part of plant life.
Rahul Mahadev Shelake, Dibyajyoti Pramanik, Jae-Yean Kim   +2 more
doaj   +1 more source

Advancements in breeding Fusarium resistant vanilla varieties using Next Generation Sequencing [PDF]

, 2019
Demand for natural vanilla flavor is increasing, but the cultivated Vanilla planifolia faces critical challenges in response to biotic and abiotic stresses. In particular, Root and Stem Rot (RSR) disease caused by Fusarium oxysporum f. sp.
Besse, Pascale, Charron, Carine, Favre, Félicien, Grisoni, Michel, Jourda, Cyril   +4 more
core  

Application of RNA silencing to plant disease resistance [PDF]

, 2012
To reduce the losses caused by plant pathogens, plant biologists have adopted numerous methods to engineer resistant plants. Among them, RNA silencing-based resistance has been a powerful tool that has been used to engineer resistant crops during the ...
Cheng-Guo Duan, Chun-Han Wang, Hui-Shan Guo   +2 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Natural history of Arabidopsis thaliana and oomycete symbioses [PDF]

, 2008
Molecular ecology of plant–microbe interactions has immediate significance for filling a gap in knowledge between the laboratory discipline of molecular biology and the largely theoretical discipline of evolutionary ecology.
A. Falk, A. H. Ellingboe, A. H. Ellingboe, A. J. Slusarenko, A. P. Rehmany, A. P. Rehmany, A. Riethmüller, A. Roetschi, Arabidopsis Genome Initiative, B. F. Holt, B. M. Tyler, C. Azevedo, C. D. Preston, C. Damgaard, D. Jirage, E. B. Holub, E. B. Holub, E. B. Holub, E. B. Holub, E. B. Holub, E. B. Holub, E. B. Holub, E. B. Holub, E. G. Bakker, E. Gäumann, E. Koch, E. O. Wilson, E. Speulman, Eric B. Holub, G. Lindau, H. Jönsson, H. Takahashi, H. Voglmayr, H.-M. Chou, J. E. Parker, J. E. Parker, J. Glazebrook, J. Glazebrook, J. M. McDowell, J. M. McDowell, J. N. Thompson, J. N. Thompson, J. N. Thompson, J. O. Borevitz, J. Silvertown, J. Song, J. Staal, J. Win, K. A. Shen, K. Century, K. Kazan, K. Lawton, K. S. Century, K. S. Thompson, L. E. Rose, M. A. Botella, M. A. Botella, M. B. Cooley, M. Damme Van, M. G. M. Aarts, M. Göker, M. H. Borhan, M. H. Borhan, M. J. Austin, M. Tör, N. Aarts, N. Gunn, O. Constantinescu, P. Ayers, P. D. Bittner-Eddy, P. Prusinkiewicz, P. R. Muskett, P. Tornero, Q. H. Shen, R. F. Warren, R. F. Warren, R. Gomulkiewicz, R. L. Allen, R. M. Clark, S. Kamoun, S. McCouch, S. R. Grant, S. Segal, T. Eulgem, T. Eulgem, T. Mitchell-Olds, W. Gassmann, X. Tang   +87 more
core   +2 more sources

Surveying the potential of secreted antimicrobial peptides to enhance plant disease resistance

Frontiers in Plant Science, 2015
Antimicrobial peptides (AMPs) are natural products found across diverse taxa as part of the innate immune system against pathogen attacks. Some AMPs are synthesized through the canonical gene expression machinery and are called ribosomal AMPs. Other AMPs
Susan Breen, P. Solomon, Frank Bedon, Delphine Vincent   +3 more
semanticscholar   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source