Results 201 to 210 of about 393,643 (259)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Recent Advances in Microfluidics for the Early Detection of Plant Diseases in Vegetables, Fruits, and Grains Caused by Bacteria, Fungi, and Viruses. [PDF]
J Agric Food ChemZhao X +10 more
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Technology from traditional knowledge - Vrikshayurveda-based expert system for diagnosis and management of plant diseases. [PDF]
J Ayurveda Integr MedRananavare LB, Chitnis S.
europepmc +1 more source
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Plant pathology and plant diseases
Plant Pathology, 2020This textbook provides a comprehensive introduction to all aspects of plant diseases, including pathogens, plant-pathogen interactions, their management, and future perspectives. Plant diseases limit potential crop production and are responsible for considerable losses in agriculture, horticulture and forestry.
Tronsmo, Anne Marte +5 more
openaire +2 more sources
Phytochemistry, 2003
The diamine putrescine and the polyamines spermidine and spermine are found in a wide range of organisms from bacteria to plants and animals. They are basic, small molecules implicated in the promotion of plant growth and development by activating the synthesis of nucleic acids.
openaire +3 more sources
The diamine putrescine and the polyamines spermidine and spermine are found in a wide range of organisms from bacteria to plants and animals. They are basic, small molecules implicated in the promotion of plant growth and development by activating the synthesis of nucleic acids.
openaire +3 more sources
2004
Pests and diseases can have direct effects on the safety, yield and quality of food grains. The food safety aspect is shown, for example, by the effects of molds that produce mycotoxins. Plant diseases may be caused by fungi, bacteria, and viruses, each having its specific means of propagation, mechanism of injury, and possibility of control.
openaire +1 more source
Pests and diseases can have direct effects on the safety, yield and quality of food grains. The food safety aspect is shown, for example, by the effects of molds that produce mycotoxins. Plant diseases may be caused by fungi, bacteria, and viruses, each having its specific means of propagation, mechanism of injury, and possibility of control.
openaire +1 more source