Results 111 to 120 of about 4,341,163 (257)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Exploring local vegetables cultivated in home gardens of Pa Tio District, Yasothon Province, Thailand: ethnobotanical knowledge, nutritional value, and horticultural potential

Journal of Ethnobiology and Ethnomedicine
Background Local vegetables are essential for food security, nutrition, and cultural practices in rural northeastern Thailand. Despite their importance, comprehensive documentation of their diversity, nutritional contributions, cultural significance, and
Piyaporn Saensouk, Surapon Saensouk, Phiphat Sonthongphithak, Khamfa Chanthavongsa, Tammanoon Jitpromma   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Diversity Stand Protest with “Diversity exists. Our center doesn’t.” shirts

, 2014
A photo of Diversity Stand protest with a group of students in “Diversity exists.
Juarez, Dominick
core   +2 more sources

Vegetative propagation of Phytolacca acinosa Roxb. by rhizome cuttings: a step towards conservation and cultivation approach

Frontiers in Conservation Science
IntroductionPhytolacca acinosa Roxb. is a highly valuable multipurpose herb native to the Himalayan region. Unsustainable harvesting of this species due to its diverse uses has resulted in a rapid decline in its population across natural habitats ...
Junaid A. Magray, Bilal A. Wani, Hanan Javid, Tajamul Islam, Aijaz H. Ganie, Roof Ul Qadir, Irshad A. Nawchoo   +6 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Antioxidant activity analysis of new interspecific hybrid germplasm thyme and oregano essential oils with different chemotypes

BMC Plant Biology
Thyme and oregano essential oils (EOs) and their components have numerous applications in the pharmaceutical, food, and cosmetic industries owing to their antioxidant, antibacterial, antifungal, anti-inflammatory, antiviral, and immunological properties.
Meiyu Sun, Jiahui Miao, Yanan Zhang, Yuanpeng Hao, Jinzheng Zhang, Hui Li, Hongtong Bai, Lei Shi   +7 more
doaj   +1 more source