Results 81 to 90 of about 305,653 (262)

Lotus Seeds: Current Molecular Biology Insights and Future Perspectives as a Prominent Biological Resource

Plants
Lotus (Nelumbo nucifera Gaertn.) is an economically and medicinally significant aquatic plant, with its seeds (lotus seeds) having attracted considerable attention due to their unique developmental traits and abundance of bioactive and nutritional ...
Jia Xin, Ruirui Li, Juan Liu, Xianbao Deng, Dong Yang, Heyun Song, Minghua Zhang, Hui Yang, Runjie He, Yapei Zhang, Heng Sun, Mei Yang   +11 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Historical Climatic Fluctuations and Geographic Isolation Shaped the Phylogeographic Patterns of a Mycoheterotrophic Species in Subtropical China

Biological Diversity
Subtropical China, dominated by evergreen broad‐leaved forests, harbors exceptionally rich and highly endemic plant diversity, yet the evolutionary history of its understory herbs remains poorly understood.
Miaomiao Shi, Tong Zeng, Zhongtao Zhao, Xiaojuan Li, Xiangping Wang, Shiran Gu, Shijin Li, Tieyao Tu, Dianxiang Zhang   +8 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Exploring local vegetables cultivated in home gardens of Pa Tio District, Yasothon Province, Thailand: ethnobotanical knowledge, nutritional value, and horticultural potential

Journal of Ethnobiology and Ethnomedicine
Background Local vegetables are essential for food security, nutrition, and cultural practices in rural northeastern Thailand. Despite their importance, comprehensive documentation of their diversity, nutritional contributions, cultural significance, and
Piyaporn Saensouk, Surapon Saensouk, Phiphat Sonthongphithak, Khamfa Chanthavongsa, Tammanoon Jitpromma   +4 more
doaj   +1 more source

Arthonia tavaresii Grube & Hafellner, a lichenicolous species on Pyrenula from India

G-Journal of Environmental Science and Technology, 2021
The present paper deals with a new record of lichenicolous fungus Arthonia tavaresii Grube & Hafellner inhabiting the lichen Pyrenula sp. from India. A brief description, distribution, and ecology of species are provided.
Gaurav K Mishra, Akhilesh Kumar Maurya, Siljo Joseph   +2 more
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source