Results 171 to 180 of about 338,261 (263)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

In-Vitro Bioactive Silver Nanoparticles Synthesized from <i>Halodule uninervis</i> Plant Extract for Multifunctional Drug Delivery. [PDF]

ACS Omega
Santhiya Selvam M, Tresina PS, Rajalakshmi R, Jeeva S, Rajeshkumar L, Sornalakshmi V, Mohan VR, Sathishkumar M.   +7 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Evaluating the efficacy of Chenopodium murale plant extract in inhibiting Streptococcus mutans and reducing dental caries risk. [PDF]

Sci Rep
Kanwal S, Perveen S, Hameed H, Tahir S, Rashid R, Raish M, Bashir S, Zaffar K, Irfan A, Kotwica-Mojzych K, Faheem S, Ahmad A, Kashif M, Bin Jardan YA.   +13 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Plant Extract in the Control of Poultry Omphalitis. [PDF]

Pathogens
Oliveira GDS, Pires PGDS, McManus C, de Jesus LM, Santos PHGS, Dos Santos VM.   +5 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Lantana camara plant extract catalyzed biosynthesis of graphene-metal nanocomposites with potential cytotoxic activities. [PDF]

PLoS One
Khan KU, Rehman M, Hameed M, Hayat K, Saeed F, Afzaal M, Akram N, Ahmed F, Asghar A, Hailu GG.   +9 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Enhanced Antimicrobial Activity of Green-Synthesized <i>Artemisia</i>-ZnO Nanoparticles: A Comparative Study with Pure ZnO Nanoparticles and Plant Extract. [PDF]

Foods
Akhras N, Çelekli A, Bozkurt H.
europepmc   +1 more source