Results 41 to 50 of about 250,508 (261)

Antibacterial Potency of Combined Extracts of Mitragyna inermis (Linn) and Monotes kerstingii (Linn) on Salmonella Typhi and Salmonella Paratyphi A and Its In vivo Toxicity against Swiss Albino Mice

UMYU Journal of Microbiology Research, 2017
The phytochemical screening, antibacterial, and toxicological effects of the extracts of Monotes kerstingii (Linn) and Mitragyna inermis (wild) were investigated. The plant extracts were prepared by the cold maceration method using water and ethanol and
Zumbes, H. J., Babalola, O. B., Nanle, C. D., Katnap, R. S., David, E. V., Anejo-Okopi, A. J., Dabo, D. A., Gokir, J. D., Nvau, J. B.   +8 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Evaluating Medicinal Plants for Anticancer Activity

The Scientific World Journal, 2014
Plants have been used for medical purposes since the beginning of human history and are the basis of modern medicine. Most chemotherapeutic drugs for cancer treatment are molecules identified and isolated from plants or their synthetic derivatives.
Elisha Solowey, Michal Lichtenstein, Sarah Sallon, Helena Paavilainen, Elaine Solowey, Haya Lorberboum-Galski   +5 more
doaj   +1 more source

Antibacterial and antioxidant strategies for acne treatment through plant extracts

Informatics in Medicine Unlocked, 2019
Acne vulgaris is a chronic skin infection affecting the majority of Indian population. There are several internal and external factors responsible for this infection.
Jaykant Vora, Anshu Srivastava, Hashmukh Modi   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Effects of pH on antioxidant and prooxidant properties of common medicinal herbs

Open Life Sciences, 2016
Background: We studied in vitro and vivo antioxidant and prooxidant abilities of aqueous extracts from Rosa canina L., Rhodiola rosea L., Hypericum perforatum L., and Gentiana lutea L.
Bayliak Maria M., Burdyliuk Nadia I., Lushchak Volodymyr I.   +2 more
doaj   +1 more source

Antifungal Effect of Some Medicinal Plant Extracts On Candida Albicans Adherence on Acrylic Resin Denture Base Material. An In Vitro Study [PDF]

Al-Rafidain Dental Journal, 2014
Evaluate the antifungal effect of some medicinal plant extracts (peppermint, rue, pomegranate and garlic) and their anti–adherent effect on C. albicans cells that attached on the fitting surface of acrylic resin denture base.
Tarik Y.Kassab -Bashi , Ghada Y.Abdul –Rahman , Nagham Hazim kassab   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Plant extracts for drug development: Is it economical?

Liaquat Medical Research Journal
Plants have been in use for medicinal purposes for centuries. A number of drugs have been developed from plant extracts and are currently in clinical practice.
Binafsha Manzoor Syed
doaj   +1 more source

Antifungal Activity in Extracts of Plants from Southwestern Oklahoma Against Aspergillus Flavus

Oklahoma Native Plant Record, 2015
The use of medicinal plants has been an integral part of human civilization since antiquity. Naturally occurring pesticidal compounds are synthesized by the plant defense system, which includes antimicrobial proteins and lower molecular weight natural ...
Tahzeeba Frisby
doaj   +1 more source