Results 51 to 60 of about 256,886 (255)

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris   +24 more
wiley   +1 more source

In vitro and in vivo antifungal activity of plant extracts against common phytopathogenic fungi

open access: yesJournal of BioScience and Biotechnology, 2022
Natural crop protection products are gaining popularity due to consumer demands and long-term toxicity of chemical pesticides. Extracts of nine locally available plants species were screened for their fungicidal activity against four widespread fungal ...
Annelore Wens, Jeroen Geuens
doaj  

Antibacterial and antioxidant strategies for acne treatment through plant extracts

open access: yesInformatics in Medicine Unlocked, 2019
Acne vulgaris is a chronic skin infection affecting the majority of Indian population. There are several internal and external factors responsible for this infection.
Jaykant Vora   +2 more
doaj   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean   +7 more
wiley   +1 more source

Anti-inflammatory and anti-nociceptive effects of hydroalchoholic extract of Nepeta menthoides on pain in aerial parts in male mice

open access: yesفصلنامه دانشگاه علوم پزشکی جهرم, 2013
Introduction: The application of herbal plants instead of synthetic drugs has been increasing in recent years because of their lower side-effects and high varieties of efficient components.
Sosan Asadi Balsin Sharif Abadi1   +3 more
doaj   +2 more sources

Evaluating Medicinal Plants for Anticancer Activity

open access: yesThe Scientific World Journal, 2014
Plants have been used for medical purposes since the beginning of human history and are the basis of modern medicine. Most chemotherapeutic drugs for cancer treatment are molecules identified and isolated from plants or their synthetic derivatives.
Elisha Solowey   +5 more
doaj   +1 more source

The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi   +7 more
wiley   +1 more source

Antifungal Activity in Extracts of Plants from Southwestern Oklahoma Against Aspergillus Flavus

open access: yesOklahoma Native Plant Record, 2015
The use of medicinal plants has been an integral part of human civilization since antiquity. Naturally occurring pesticidal compounds are synthesized by the plant defense system, which includes antimicrobial proteins and lower molecular weight natural ...
Tahzeeba Frisby
doaj   +1 more source

Administering Blinatumomab via Continuous Intravenous Infusion in Pediatric Patients—A Single‐Institution Retrospective Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab, a CD19xCD3 bispecific T‐cell engager, has become standard therapy for children with de novo B‐cell acute lymphoblastic leukemia (B‐ALL). This retrospective review describes the experience of blinatumomab administration in pediatric patients.
Julia M. Hurley   +6 more
wiley   +1 more source

Effects of pH on antioxidant and prooxidant properties of common medicinal herbs

open access: yesOpen Life Sciences, 2016
Background: We studied in vitro and vivo antioxidant and prooxidant abilities of aqueous extracts from Rosa canina L., Rhodiola rosea L., Hypericum perforatum L., and Gentiana lutea L.
Bayliak Maria M.   +2 more
doaj   +1 more source

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