Results 71 to 80 of about 250,508 (261)

Cardioprotective Plant Extracts

International Journal of Innovative Technology and Exploring Engineering, 2019
Cardiovascular disease is assumingas a major cause of morbidity and mortality worldwide. In traditional Indian medicinal system, many plants were used for thetreatment of cardiac failure. Medicinalplants are used in various ailments due to efficacy,low cost, ease availability and safety.Because of these advantages the usage ofmedicinal plant increased ...
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Synthesis of silver nanoparticle using Portulaca oleracea L. extracts [PDF]

Nanomedicine Journal, 2013
Objective(s): To evaluate the influences of aqueous extracts of plant parts (stem, leaves, and root) of Portulaca oleracea L. on bioformation of silver nanoparticles (AgNPs).
Shahbazi Nafeseh, Varshosaz Jaleh, Asghari Gholamreza   +2 more
doaj   +2 more sources

Ceramides Extracted from Wool: Pilot Plant Solvent Extraction

Textile Research Journal, 2008
Ceramides extracted from wool fibers have proved to be beneficial in pharmaceutical and cosmetic formulations in the treatment and care of skin and human hair. This work sought to obtain internal wool lipid extract enriched in ceramides at pilot plant level without causing significant damage to the wool fiber. To this end, two extraction methodologies
Ramírez, Raquel, Martí, Meritxell, Manich, Albert M., Parra Juez, José Luis, Cordech Negra, Luisa   +4 more
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Efecto antimicrobiano de hojas de Melaleuca leucadendron L, que crece en la Ciénaga de Zapata Antimicrobial effect of the leaves of Melaleuca leucadendron L growing in Cienaga de Zapata

Revista Médica Electrónica, 2010
SUMARY Melaleuca leucadendron L is a tree commonly known as cayeput, being an invasive, undesirable species in Cienaga de Zapata, in the province of Matanzas. According to the referred usages, it might be exploited in a reasonable way as an antimicrobial
doaj  

Plant Extract v1

, 2018
A plant extract is a substance or active substance of a desired property extracted from plant tissue by treatment for a specific purpose. Plant extracts can be used in a variety of areas including health foods, therapeutic drugs, cosmetics, processing aids, additives - chemical alternatives, and so on.
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source