Results 71 to 80 of about 3,188,076 (295)

Plant extracts for drug development: Is it economical?

Liaquat Medical Research Journal
Plants have been in use for medicinal purposes for centuries. A number of drugs have been developed from plant extracts and are currently in clinical practice.
Binafsha Manzoor Syed
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Screening of selected indigenous plant species for their anti-inflammatory properties [PDF]

BIO Web of Conferences
Most plant extracts are used in traditional medicine as antibacterial, antioxidant, anti-inflammatory and antidiabetic. In this study, the anti-inflammatory properties of plant extracts were studied.
Mukhammedov Ikboljon, Yusupov Ulugbek, Abdusamatov Sokhibjon   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Plant Extracts [PDF]

, 2016
Tragopogon porrifolius, commonly referred to as white salsify, is an edible herb used in folk medicine to treat cancer. Samples of Tragopogon porrifolius plant grown wild in Palestine were extracted with different solvents: water, 80% ethanol, and 100 ...
Zaidoun Salah, Warad, Ismail, Khalid, Mahmoud F., Mahmoud F. Khalid, Sharehan H. Ariqat, Ismail Warad, Fuad Al-Rimawi, Ariqat, Sharehan H., Rishmawi, Suzi, Salah, Zaidoun, Suzi Rishmawi, Al-Rimawi, Fuad   +11 more
core   +1 more source

Anti-inflammatory and anti-nociceptive effects of hydroalchoholic extract of Nepeta menthoides on pain in aerial parts in male mice

فصلنامه دانشگاه علوم پزشکی جهرم, 2013
Introduction: The application of herbal plants instead of synthetic drugs has been increasing in recent years because of their lower side-effects and high varieties of efficient components.
Sosan Asadi Balsin Sharif Abadi1, Sima Nasri, Gholamreza Amin, Sayeh Bidaran   +3 more
doaj   +2 more sources

Antibacterial Potency of Combined Extracts of Mitragyna inermis (Linn) and Monotes kerstingii (Linn) on Salmonella Typhi and Salmonella Paratyphi A and Its In vivo Toxicity against Swiss Albino Mice

UMYU Journal of Microbiology Research, 2017
The phytochemical screening, antibacterial, and toxicological effects of the extracts of Monotes kerstingii (Linn) and Mitragyna inermis (wild) were investigated. The plant extracts were prepared by the cold maceration method using water and ethanol and
Zumbes, H. J., Babalola, O. B., Nanle, C. D., Katnap, R. S., David, E. V., Anejo-Okopi, A. J., Dabo, D. A., Gokir, J. D., Nvau, J. B.   +8 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Phytochemicals/Plant Extracts as Corrosion Inhibitors for Magnesium in H2SO4Solutions

This chapter provides a comprehensive overview of utilizing phytochemicals and plant extracts as green, sustainable corrosion inhibitors for magnesium metal in contact with sulfuric acid (H2SO4) solutions.
Berdimuradov, Khasan, Kholikov, Abduvali, Akbarov, Khamdam, Es-Soufi, Hicham, Berdimurodov, Elyor, Ibrahimi, Brahim El, Tuzun, Burak   +6 more
core   +1 more source