Results 111 to 120 of about 327,235 (306)

Development of a Synthetic 3D Platform for Compartmentalized Kidney In Vitro Disease Modeling

Advanced Healthcare Materials, EarlyView.
A fully synthetic, compartmentalized 3D kidney disease model is introduced. The kidney model combines a PEG‐based hydrogel matrix with anisotropic, enzymatically degradable rod‐shaped microgels to spatially arrange a triple co‐culture of key renal epithelial, endothelial, and fibroblast cells.
Ninon Möhl, Daphne Bouwens, Johanna Abele, Aline Hans, Tanja Topic, Daniel Günther, Jitske Jansen, Rafael Kramann, Laura De Laporte   +8 more
wiley   +1 more source

The role of climate and plant functional trade-offs in shaping global biome and biodiversity patterns

, 2011
Aim: Two of the oldest observations in plant geography are the increase in plant diversity from the poles towards the tropics and the global geographic distribution of vegetation physiognomy (biomes). The objective of this paper is to use a process-based
Ackerly, Anderson, Betts, Box, Box, Currie, Diaz, Ehleringer, Field, Francis, Garnier, Grime, Hawkins, Hillebrand, Holdridge, Kier, Kleidon, Kleidon, Kreft, Köppen, Lavorel, Legendre, Mittelbach, Mokany, Monserud, Neilson, Olson, Pausas, Petchey, Prentice, Rahbek, Ramankutty, Raunkiaer, Reich, Reineking, Schimper, Schwinning, Sheffield, Thornley, Tilman, Tilman, Violle, von Humboldt, Westoby, Whittaker, Williams, Woodward, Woodward   +47 more
core   +1 more source

Efficient cell reprogramming as a target for functional-marker strategies? Towards new perspectives in applied plant-nutrition research [PDF]

, 2005
The review aims at visualizing and strengthening approximation of current strategies in plant breeding, plant nutrition, and molecular biology. Innovations in new breeding strategies on quantitative traits are based on the development of functional DNA ...
Arnholdt-Schmitt, Birgit
core   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

Automating Vascular Biology: An End‐to‐End Automated Workflow for High‐Throughput Blood Vessel‐on‐a‐Chip Production and Multi‐Site Validation

Advanced Healthcare Materials, EarlyView.
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin, Hanieh Mohammad Hashemi, Kimia Asadi Jozani, Anushree Chakravarty, Sonya Kouthouridis, Jessica Bonanno, Nicky Anvari, Shravanthi Rajasekar, Feng Zhang, Richard Y. Cheng, Narendra Kumar Singh, Luis Miguel Medina, Marc Durante, Yufang He, Boyang Zhang   +14 more
wiley   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

IDENTIFICATION OF THE MAIN FUNCTIONAL GROUPS IN THE DRY GRASSLANDS OF FESTUCETALIA VALESIACAE FROM NORTH-EASTERN ROMANIA [PDF]

Journal of Plant Development, 2015
Plant functional traits and plant functional groups are increasingly used to assess the effect of the change in land use on plant species or plant communities, in nature conservation projects, to detect patterns in the expansion some invasive species or ...
Constantin MARDARI, Cătălin TĂNASE
doaj  

Plant responses to belowground variations along elevational gradients in temperate and tropical climates [PDF]

, 2019
Soil is a hyper-heterogeneous environment, and how plants respond to changes in belowground variations in soil properties and microclimate is poorly understood.
Angeles, Guillermo, Anthelme, Fabien, Bounous, Manon, Cruz, Nereyda, Fourtier, Stephane, Freschet, Grégoire T., Jimenez, Leonore, Mao, Zhun, Marin-Castro, Beatriz, Merino-Martin, Luis, Mohamed, Awaz, Morales-Martinez, Marco, Rey, Hervé, Roumet, Catherine, Sieron, Katrin, Stokes, Alexia, Weemstra, Monique   +16 more
core  

Quantitative Genetics and Functional-Structural Plant Growth Models: Simulation of Quantitative Trait Loci Detection for Model Parameters and Application to Potential Yield Optimization

, 2008
Background and Aims: Prediction of phenotypic traits from new genotypes under untested environmental conditions is crucial to build simulations of breeding strategies to improve target traits.
Cournède, Paul-Henry, Courtois, Brigitte, De Reffye, Philippe, Letort, Veronique, Mahe, Paul   +4 more
core   +5 more sources

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source