Results 211 to 220 of about 2,082,531 (360)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Recycling waste via insect agriculture: Frass impacts on soil and plant health. [PDF]
Amorim HCS +8 more
europepmc +1 more source
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Editorial: Soil-root-microbe interactions promote soil and plant health. [PDF]
Sun B, Barnes AD.
europepmc +1 more source
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Retraction notice to "Beyond correlation: Understanding the causal link between microbiome and plant health" [Heliyon 10 (2024) e40517]. [PDF]
Olanrewaju OS, Glick BR, Babalola OO.
europepmc +1 more source
Microbial Effectors: Key Determinants in Plant Health and Disease. [PDF]
Todd JNA +3 more
europepmc +1 more source

