Results 41 to 50 of about 291,543 (298)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Growth and Hormonal Responses to Salicylic Acid and Calcium Chloride Seed Priming in Domestic and Wild Salt-Tolerant Barley Species Under Saline Conditions

Plants
Salinity is among the main abiotic constraints limiting crop productivity worldwide. Salt tolerance can be improved by introducing adaptive traits from wild species and enhancing pre-existing salt-adaptive mechanisms through priming. This study evaluated
Rim Ben Youssef, Nahida Jelali, Purificación Andrea Martínez-Melgarejo, Alfonso Albacete, Chedly Abdelly, Francisco Pérez-Alfocea, Cristina Martínez-Andújar   +6 more
doaj   +1 more source

Transcriptome Approach Reveals the Response Mechanism of Heimia myrtifolia (Lythraceae, Myrtales) to Drought Stress

Frontiers in Plant Science, 2022
Drought is a major environmental condition that inhibits the development and cultivation of Heimia myrtifolia. The molecular processes of drought resistance in H. myrtifolia remain unknown, which has limited its application.
Lin Lin, Lin Lin, Lin Lin, Jie Wang, Jie Wang, Jie Wang, Qun Wang, Qun Wang, Qun Wang, Mengcheng Ji, Mengcheng Ji, Mengcheng Ji, Sidan Hong, Sidan Hong, Sidan Hong, Linxue Shang, Linxue Shang, Linxue Shang, Guozhe Zhang, Guozhe Zhang, Guozhe Zhang, Yu Zhao, Yu Zhao, Yu Zhao, Qingqing Ma, Qingqing Ma, Qingqing Ma, Cuihua Gu, Cuihua Gu, Cuihua Gu   +29 more
doaj   +1 more source

Production of mutants affected in hormone signalling to dissect defence mechanisms in Hevea brasiliensis: the case of ethylene [PDF]

, 2012
Production of mutants by genetic transformation is one alternative to dissect the response to hormonal treatment. Ethylene is an important plant hormone involved in latex production.
Dessailly, Florence, Leclercq, Julie, Lorenzini, Eve, Martin, Florence, Montoro, Pascal, Rio, Maryannick   +5 more
core  

Negative feedback control of jasmonate signaling by an alternative splice variant of JAZ10 [PDF]

, 2013
The plant hormone jasmonate (JA) activates gene expression by promoting ubiquitin-dependent degradation of JAZ transcriptional repressor proteins. A key feature of all JAZ proteins is the highly conserved Jas motif, which mediates both JAZ degradation ...
Campos, Marcelo L., Chung, Hoo Sun, He, Sheng Hang, Howe, Gregg A., Moreno, Javier Edgardo, Patel, Lalita C., Shyu, Christine, Yao, Jian   +7 more
core   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

A point‐to‐point protein–protein interaction assay reveals the signaling interplays among plant hormones and environmental cues

Plant Direct, 2020
As sessile organisms, plants must properly coordinate their growth and developmental programs with changes in the environment. The integration of exogenous environmental cues with endogenous plant hormone responses often occurs through physical protein ...
Kaiwen Sun, Xiangwen Xue, Nana Liu, Ziqiang Zhu, Hong Li   +4 more
doaj   +1 more source

Comparative Transcriptome Analysis Provides Molecular Insights into the Interaction of Beet necrotic yellow vein virus and Beet soil-borne mosaic virus with Their Host Sugar Beet

Viruses, 2020
Beet necrotic yellow vein virus (BNYVV) and Beet soil-borne mosaic virus (BSBMV) are closely related species, but disease development induced in their host sugar beet displays striking differences.
Jose Fernando Gil, Daniel Wibberg, Omid Eini, Eugene I. Savenkov, Mark Varrelmann, Sebastian Liebe   +5 more
doaj   +1 more source

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich, Manali Zope, Peter M. Fantozzi, Cassie N. Kline, Iris Paltin, Matthew C. Hocking   +5 more
wiley   +1 more source

Adaptive and metabolic convergence in rhizosphere and gut microbiomes

Microbiome
Microbial ecosystems such as the plant rhizosphere and the human gut microbiome are crucial for the health and functionality of their hosts. Despite their differences, these ecosystems share core evolutionary principles shaped by agriculture, lifestyle ...
Diana Ilyaskina, Safaa Altveş, Lemeng Dong, Harro Bouwmeester, Sahar El Aidy   +4 more
doaj   +1 more source