Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
On the plant growth hormone produced by Rhizopus suinus [PDF]
, 1935 Since it was first discovered that cell elongation in the Avena coleoptile is controlled by a hormone, our understanding of the nature and rôle of this substance has progressed considerably. Apart from the elucidation of its functions in promoting growth,
Thimann, Kenneth V.
core
Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene [PDF]
, 2012 Background : The phytohormone ethylene is involved in a wide range of developmental processes and in mediating plant responses to biotic and abiotic stresses.
Bouzayen, Mondher +10 more
core +5 more sources
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Exogenous Gibberellic Acid Ameliorates Salinity-Induced Morphological and Biochemical Alterations in Portulaca grandiflora [PDF]
Planta Daninha, 2018 : An investigation was carried out to estimate the NaCl stress and ameliorative effects of Gibberellic Acid (GA3) on Portulaca grandiflora Hook. A crop experiment was conducted (CRBD) where all the pots were irrigated to field capacity.
A.S.A.S. SHAIKHA +4 more
doaj +1 more source
Reference Profile Correlation Reveals Estrogen-like Trancriptional Activity of Curcumin [PDF]
, 2010 Background: Several secondary metabolites from herbal nutrient products act as weak estrogens (phytoestrogens), competing with endogenous estrogen for binding to the estrogen receptors and inhibiting steroid converting enzymes.
Albini, Adriana +9 more
core +1 more source
An ectomycorrhizal fungus alters sensitivity to jasmonate, salicylate, gibberellin, and ethylene in host roots. [PDF]
, 2020 The phytohormones jasmonate, gibberellin, salicylate, and ethylene regulate an interconnected reprogramming network integrating root development with plant responses against microbes.
Amirebrahimi, Mojgan +14 more
core +3 more sources
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Field resistance to Orobanche crenata in pea (Pisum sativum L.): beyond strigolactones
BMC Plant BiologyBackground Orobanchaceae are parasitic weeds causing substantial yield losses in many crops, including pea (Pisum sativum L.). Within host species, genotypes that display enhanced resistance to Orobanchaceae often exude low levels of strigolactones (SLs)
Francesco Arcieri +12 more
doaj +1 more source
Cell polarity and patterning by PIN trafficking through early endosomal compartments in Arabidopsis thaliana [PDF]
, 2013 PIN-FORMED (PIN) proteins localize asymmetrically at the plasma membrane and mediate intercellular polar transport of the plant hormone auxin that is crucial for a multitude of developmental processes in plants.
De Rycke, Riet +8 more
core +5 more sources