Results 161 to 170 of about 2,659,565 (304)

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Inheritance of breeding system in Cakile (Brassicaceae) following hybridization: implications for plant invasions. [PDF]

Ann Bot, 2020
Li C, Mesgaran MB, Ades PK, Cousens RD.
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Plant Invasions in Nepal: What We Do Not Know?

Plant Invasions in Nepal: What We Do Not ...
Mohan Pandey (18060766), Bharat Babu Shrestha (8680041), Anju Sharma Poudel (8680038)   +2 more
core  

Plant invasions under accumulating global change factors

Many ecosystems face numerous concurrent global change factors (GCFs), each of which may impact various ecological processes. However, how accumulating GCFs jointly influence plant invasions remains unknown.
van Kleunen, Mark, Shi, Xiong, Liu, Yanjie   +2 more
core   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Biological Invasions: A Growing Burden on Health and Finances

Field Actions Science Reports
Recognized as one of the five major drivers of biodiversity change globally by the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES),1 biological invasions are a major and increasing challenge to biodiversity in ...
Christophe Diagne, Franck Courchamp
doaj  

El fuego favorece la invasión de Teline monspessulana (Fabaceae) al aumentar su germinación Fire promotes Teline monspessulana (Fabaceae) invasion by increasing its germination

Revista Chilena de Historia Natural, 2010
A nivel mundial, se ha reportado que las especies invasoras y el fuego pueden interactuar positivamente modificando la dinámica del paisaje y los ciclos ecosistémicos.
RAFAEL A GARCÍA, ANÍBAL PAUCHARD, LOHENGRIN A CAVIERES, EDUARDO PEÑA, MARÍA F RODRÍGUEZ   +4 more
doaj  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source