Results 161 to 170 of about 488,682 (310)

A practical green synthesis method of Ag NPs using rosy periwinkle plant leaves for solar panel coating. [PDF]

Heliyon, 2023
Palanichamy P, Krishnasamy R, Meenakshi Sundaram U, Thiagamani SMK, Ilyas RA, Hassan AM.   +5 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Erratum to "Phenotypic Analysis of Diseased Plant Leaves Using Supervised and Weakly Supervised Deep Learning". [PDF]

Plant Phenomics, 2023
Zhou L, Xiao Q, Taha MF, Xu C, Zhang C.
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Method for CaOx crystals isolation from plant leaves. [PDF]

MethodsX, 2022
Cerritos-Castro IT, Patrón-Soberano A, Barba de la Rosa AP.   +2 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Comparative study of hexane extract for volatile and non volatile components of leaves and rhizomes of Acorus calamus linn. using high performance thin layer chromatography (HPTLC)

Journal of Applied Pharmaceutical Research, 2014
The present communication attempts to evaluate the comparative study of leaves and rhizomes of Acorus calamus Linn. (Family; Araceae) using High Performance Thin Layer Chromatography (HPTLC).
AS Bisht, Monika Chauhan, A Joshi, Y Joshi, A Dimri, V Singh, D Juyal   +6 more
doaj  

Nutritional Enrichment of Plant Leaves by Combining Genes Promoting Tocopherol Biosynthesis and Storage. [PDF]

Metabolites, 2023
Morelli L, García Romañach L, Glauser G, Shanmugabalaji V, Kessler F, Rodriguez-Concepcion M.   +5 more
europepmc   +1 more source

The role of a Polyphenol from Myrothamnus flabellifolius in the protection of membranes during desiccation-using liposomes as a model membrane system

, 2002
Includes bibliographical references.A deficiency of water is a common stress experienced by plants. Dehydration of plant tissue results in altered protein and lipid ultrastructure responsible for membrane stabilisation leading inevitably to the death of ...
Westalle, Kim Louise
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source