Results 161 to 170 of about 12,351 (247)

The Lectin from <i>Schinus terebinthifolia</i> Raddi Leaves (SteLL) Exhibited Anti-Inflammatory Activity in Lipopolysaccharide-Induced Acute Lung Injury in Mice. [PDF]

open access: yesInt J Mol Sci
Marinho AO   +9 more
europepmc   +1 more source

The use of deidentified organ donor testes for research

open access: yesAndrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova   +4 more
wiley   +1 more source

Jacalin-Related Lectin <i>OsJacLK1</i> Positively Regulates Resistance to <i>Magnaporthe oryzae</i> in Rice. [PDF]

open access: yesPlants (Basel)
Chen B   +9 more
europepmc   +1 more source

Slit2/Robo Signaling Restores Diabetic Erectile Function via Neurovascular Remodeling

open access: yesAndrology, EarlyView.
ABSTRACT Background Diabetes mellitus‐induced erectile dysfunction (DMED) is a common and debilitating vascular‐neurogenic complication of diabetes. The poor responsiveness of DMED patients to phosphodiesterase type‐5 inhibitors underscores the need for therapies capable of restoring both endothelial integrity and cavernous nerve function.
Sen Fu   +7 more
wiley   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

open access: yesBritish Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu   +6 more
wiley   +1 more source

Targeting KRAS for cancer therapy

open access: yesBritish Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia   +4 more
wiley   +1 more source

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