Results 171 to 180 of about 12,351 (247)

Comparative Analysis of Banana Lectins rBanLec-Like and H84T-BanLec: An In Silico and In Vitro Approach. [PDF]

Protein J
de Sousa GF, Gonçalves CN, de Oliveira Della Senta D, de Souza CG, de Lima AC, Rodrigues JC, Legendre M, Markovitz DM, da Silva Pinto L.   +8 more
europepmc   +1 more source

Plant lectins, from ancient sugar-binding proteins to emerging anti-cancer drugs in apoptosis and autophagy. [PDF]

Cell Prolif, 2015
Jiang QL, Zhang S, Tian M, Zhang SY, Xie T, Chen DY, Chen YJ, He J, Liu J, Ouyang L, Jiang X.   +10 more
europepmc   +1 more source

Garadacimab for the long‐term prophylaxis of hereditary angioedema

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Hereditary angioedema (HAE), a rare and debilitating disease characterized by recurrent and spontaneous attacks of tissue swelling, has a high unmet therapeutic need, with many patients experiencing insufficient disease control with current prophylactic treatments.
Emel Aygören‐Pürsün, Regina Treudler, Petra Staubach, Inmaculada Martinez Saguer, Thomas Linhoff, Markus Magerl   +5 more
wiley   +1 more source

The Entomotoxic Fungal Lectin <i>Marasmius oreades</i> Agglutinin Disrupts the Midgut Epithelium of Colorado Potato Beetle Larvae. [PDF]

J Agric Food Chem
Žigon P, Bogataj U, Praček S, Peternel T, Mrak P, Smodiš Škerl MI, Ladányi M, Karničar K, Fonović M, Panevska A, Skočaj M, Turk D, Žnidaršič N, Razinger J, Sabotič J.   +14 more
europepmc   +1 more source

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

The FEBS Journal, EarlyView.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna, Alessandro Cherubini, Ersilia Varone, Serena Germani, Alice Marrazza, Ester Zito   +5 more
wiley   +1 more source

Lectin-Rose Bengal Conjugates for Targeted Photodynamic Inactivation of Pathogenic Bacteria. [PDF]

Int J Mol Sci
Atrash M, Hovor I, Nisnevitch M, Nakonechny F.   +3 more
europepmc   +1 more source

Effect of algae and plant lectins on planktonic growth and biofilm formation in clinically relevant bacteria and yeasts. [PDF]

Biomed Res Int, 2014
Vasconcelos MA, Arruda FV, Carneiro VA, Silva HC, Nascimento KS, Sampaio AH, Cavada B, Teixeira EH, Henriques M, Pereira MO.   +9 more
europepmc   +1 more source

Biogenesis of TNF‐α‐insights into proteostasis and inflammation

The FEBS Journal, EarlyView.
TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar, Céline Philippe, Eric Chevet, Jiří Zahradník   +3 more
wiley   +1 more source

Cryo‐EM structure of GH43 β‐Xylosidase from Enterobacter cloacae provides insights into substrate specificity and the role of an auxiliary domain in enzymatic activity

The FEBS Journal, EarlyView.
Xylan, the second most abundant plant cell wall polysaccharide, is degraded by β‐xylanases and β‐xylosidases. Here, we present the 2.65 Å cryo‐EM structure of Enterobacter cloacae β‐xylosidase (EcXyl43, GH43) and the 2.4 Å X‐ray structure of its inactive F507A mutant.
Lorenzo Briganti, Andre Schutzer Godoy, Caio Cesar Mello Capetti, Rafaela Sachetto Fernandes, Vanessa O. A. Pellegrini, Ornella M. Ontañon, Eleonora Campos, Rodrigo V. Portugal, Igor Polikarpov   +8 more
wiley   +1 more source

Altering the carbohydrate-binding specificity of the legume lectin FRIL through structure-guided engineering. [PDF]

Nat Commun
Liu YM, Nguyen HTV, Chen X, Shahed-Al-Mahmud M, Chen TH, Liao KS, Lo JM, Kan TC, Ren CT, Ma C.   +9 more
europepmc   +1 more source