Results 261 to 270 of about 31,393 (338)

Proteins from Edible Mushrooms: Nutritional Role and Contribution to Well-Being. [PDF]

Foods
Ionescu M, Dincă MN, Ferdeș M, Zăbavă BȘ, Paraschiv G, Moiceanu G.   +5 more
europepmc   +1 more source

Structural and functional characterization of the newly identified Photorhabdus laumondii tumor necrosis factor‐like lectin

The FEBS Journal, EarlyView.
We characterize the PLTL lectin from Photorhabdus laumondii, which adopts a unique TNF‐like fold. Binding assays reveal a preference for branched histo‐blood group oligosaccharides. Protein crystallography uncovers a novel hexameric assembly and identifies key residues involved in carbohydrate recognition.
Filip Melicher, Pavel Dobeš, Jan Komárek, Lukáš Faltinek, Marek Korsák, Petra Sýkorová, Josef Houser, Michaela Wimmerová   +7 more
wiley   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Influence of pH, ion composition and carbohydrate recognition on the attachment of <i>Cryptosporidium parvum</i> to lamb<b>'</b>s lettuce. [PDF]

Curr Res Parasitol Vector Borne Dis
Kubina S, Costa D, Villena I, Favennec L, La Carbona S, Razakandrainibe R.   +5 more
europepmc   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

The fc fragment of IgMs binds C1q to activate the first step of the classical complement pathway, while inhibiting complement‐dependent cytotoxicity

The FEBS Journal, EarlyView.
Multimeric IgM‐fragment crystallizable region (Fc) fragments retain the ability to bind C1q and initiate the classical complement pathway, leading to C4 activation and deposition in vitro. However, the Fc cores can also inhibit complement‐dependent cytotoxicity by competing with surface‐bound antibodies for C1q engagement.
Andrea J. Pinto, Anne Chouquet, Isabelle Bally, Véronique Rossi, Nicole M. Thielens, Chantal Dumestre‐Pérard, Renate Kunert, Christine Gaboriaud, Wai Li Ling, Jean‐Baptiste Reiser   +9 more
wiley   +1 more source

Genome-wide characterization and expression analysis of the JRL gene family in response to hormones and abiotic stress in tomato (<i>Solanum lycopersicum</i> L.). [PDF]

PeerJ
Li H, Hu H, Cao L, Zhuo Y, Wang L, Ma H, Zhong M.   +6 more
europepmc   +1 more source

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

The FEBS Journal, EarlyView.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna, Alessandro Cherubini, Ersilia Varone, Serena Germani, Alice Marrazza, Ester Zito   +5 more
wiley   +1 more source

Bridging Viral Glycobiology and Lectin Biotechnology for Antiviral and Diagnostic Strategies. [PDF]

ACS Bio Med Chem Au
Cavada BS, Osterne VJS, Oliveira MV, Ferreira WP, Neto CC, Nascimento KS, Pinto-Junior VR.   +6 more
europepmc   +1 more source

Applying Plant Lectins to Assay the Effect of Environmental Pollution on the Glycosylation of Human Placenta

, 2005
Grażyna Końska, Anna Pituch‐Noworolska, G. Kaczmarczyk, K. Tyrkalska, L Zamorska, Jacques Guillot   +5 more
openalex   +1 more source