Results 1 to 10 of about 2,150,147 (255)

C-type lectin receptor signaling in schistosomiasis [PDF]

Frontiers in Immunology
Schistosomiasis is a major neglected tropical disease caused by helminth parasites of the genus Schistosoma, affecting over 250 million people worldwide and leading to substantial morbidity primarily driven by egg-induced immunopathology.
Santoshi Chaudhary, Parisa Kalantari
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The multiple roles of C-type lectin receptors in cancer [PDF]

Frontiers in Oncology, 2023
C-type lectin receptors are a family of immune response receptors that can bind with a broad repertoire of ligands. It can function as innative immune receptors to surveillance bacteria, fungi, and virus invasions.
Qiao Li
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Orientia tsutsugamushi binds to multiple C-type lectin receptors [PDF]

Infection and Immunity
Orientia tsutsugamushi, the agent of scrub typhus, is an obligate intracellular bacterium whose atypical cell wall lacks many classical pathogen-associated molecular patterns but is enriched in neutral glycans.
Véronique Hefter, Sabine Mayer-Lambertz, Zacharias Orfanos, Jonas Mehl, Bernd Lepenies, Christian Keller   +5 more
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Secondary Immune Surveillance via upregulation of C-type lectin receptors [PDF]

npj Gut and Liver
C-type lectin receptors (CLRs) are a family of pattern recognition receptors that sense diverse microbial and damage-associated molecular patterns. Many CLRs, like Mincle and Dectin-3, are upregulated by TLR4 signaling.
Farhin Patel, Emmanuel Boafo, Yurui Zheng, Colin Varnet, Adam Kim   +4 more
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C-type lectin-like receptor 2: roles and drug target [PDF]

Thrombosis Journal
C-type lectin-like receptor-2 (CLEC-2) is a member of the C-type lectin superfamily of cell surface receptors. The first confirmed endogenous and exogenous ligands of CLEC-2 are podoplanin and rhodocytin, respectively.
Lan Sun, Zhe Wang, Zhiyan Liu, Guangyan Mu, Yimin Cui, Qian Xiang   +5 more
doaj   +2 more sources

C-Type Lectin Receptors in Asthma

Frontiers in Immunology, 2018
Asthma is a heterogeneous disease that affects approximately 300 million people worldwide, largely in developed countries. The etiology of the disease is poorly understood, but is likely to involve specific innate and adaptive responses to inhaled ...
Sabelo Hadebe, Sabelo Hadebe, Frank Brombacher, Frank Brombacher, Gordon D. Brown, Gordon D. Brown   +5 more
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Targeting C-type lectin-like molecule-1 for antibody-mediated immunotherapy in acute myeloid leukemia

Haematologica, 2010
Background C-type lectin-like molecule-1 is a transmembrane receptor expressed on myeloid cells, acute myeloid leukemia blasts and leukemic stem cells.
Xiaoxian Zhao, Shweta Singh, Cecile Pardoux, Jingsong Zhao, Eric D. Hsi, Arie Abo, Wouter Korver   +6 more
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Can Plant Lectins Help to Elucidate Insect Lectin-Mediated Immune Response?

Insects, 2021
Lectins are carbohydrate-binding proteins that recognize and selectively bind to specific sugar structures. This group of proteins is widespread in plants, animals, and microorganisms, and exerts a broad range of functions.
Pengyu Chen, Kristof De Schutter, Els J. M. Van Damme, Guy Smagghe   +3 more
doaj   +1 more source

Association of circulating soluble lectin-like oxidized low-density lipoprotein receptor-1 with inflammatory markers and urinary albumin excretion in patients with type 2 diabetes

SAGE Open Medicine, 2021
Objectives: The main purpose of the study was to study the association between circulating soluble lectin-like oxidized low-density lipoprotein receptor-1 levels and various markers, including inflammatory markers such as high-sensitivity C-reactive ...
Kohzo Takebayashi, Tatsuhiko Suzuki, Mototaka Yamauchi, Kenji Hara, Takafumi Tsuchiya, Toshihiko Inukai, Koshi Hashimoto   +6 more
doaj   +1 more source

Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptors. [PDF]

PLoS ONE, 2013
Mannose-binding lectin (MBL) is a key soluble effector of the innate immune system that recognizes pathogen-specific surface glycans. Surprisingly, low-producing MBL genetic variants that may predispose children and immunocompromised individuals to ...
Matthew Brudner, Marshall Karpel, Calli Lear, Li Chen, L Michael Yantosca, Corinne Scully, Ashish Sarraju, Anna Sokolovska, M Reza Zariffard, Damon P Eisen, Bruce A Mungall, Darrell N Kotton, Amel Omari, I-Chueh Huang, Michael Farzan, Kazue Takahashi, Lynda Stuart, Gregory L Stahl, Alan B Ezekowitz, Gregory T Spear, Gene G Olinger, Emmett V Schmidt, Ian C Michelow   +22 more
doaj   +1 more source