Results 31 to 40 of about 2,150,147 (255)

Key thermally dimorphic fungal pathogens: shaping host immunity

Open Biology, 2022
Exposure to fungal pathogens from the environment is inevitable and with the number of at-risk populations increasing, the prevalence of invasive fungal infection is on the rise. An interesting group of fungal organisms known as thermally dimorphic fungi
Maxine A. Höft, Lucian Duvenage, J. Claire Hoving   +2 more
doaj   +1 more source

C-type Lectin CD209L/L-SIGN and CD209/DC-SIGN: Cell Adhesion Molecules Turned to Pathogen Recognition Receptors

Biology, 2020
Simple Summary COVID-19 pandemic continues to pose a serious threat to global public health with overwhelming worldwide socio-economic disruption. SARS-CoV-2, the viral agent of COVID-19, uses its surface glycoprotein Spike (S) for host cell attachment ...
N. Rahimi
semanticscholar   +1 more source

A C-type lectin from Bothrops jararacussu venom disrupts Staphylococcal biofilms. [PDF]

PLoS ONE, 2015
Bovine mastitis is a major threat to animal health and the dairy industry. Staphylococcus aureus is a contagious pathogen that is usually associated with persistent intramammary infections, and biofilm formation is a relevant aspect of the outcome of ...
Raphael Contelli Klein, Mary Hellen Fabres-Klein, Leandro Licursi de Oliveira, Renato Neves Feio, François Malouin, Andréa de Oliveira Barros Ribon   +5 more
doaj   +1 more source

Information transfer in mammalian glycan-based communication

eLife, 2023
Glycan-binding proteins, so-called lectins, are exposed on mammalian cell surfaces and decipher the information encoded within glycans translating it into biochemical signal transduction pathways in the cell.
Felix F Fuchsberger, Dongyoon Kim, Natalia Baranova, Hanka Vrban, Marten Kagelmacher, Robert Wawrzinek, Christoph Rademacher   +6 more
doaj   +1 more source

Targeting C-type Lectin Receptors for Cancer Immunity

Frontiers in Immunology, 2015
C-type lectin receptors (CLRs) are a large family of soluble and trans-membrane pattern recognition receptors that are widely and primarily expressed on myeloid cells.
Huimin eYan, Huimin eYan, Tomomori eKamiya, Tomomori eKamiya, Papawee eSuabjakyong, Papawee eSuabjakyong, Noriko M Tsuji   +6 more
doaj   +1 more source

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

Journal of Experimental Medicine, 2009
Tuberculosis remains a fatal disease caused by Mycobacterium tuberculosis, which contains various unique components that affect the host immune system. Trehalose-6,6′-dimycolate (TDM; also called cord factor) is a mycobacterial cell wall glycolipid that ...
E. Ishikawa, Tetsuaki Ishikawa, Y. Morita, K. Toyonaga, H. Yamada, O. Takeuchi, T. Kinoshita, S. Akira, Y. Yoshikai, S. Yamasaki   +9 more
semanticscholar   +1 more source

Diet-induced reconstruction of mucosal microbiota associated with alterations of epithelium lectin expression and regulation in the maintenance of rumen homeostasis

Scientific Reports, 2017
It is unknown whether lectins of the rumen epithelium contribute to the recognition of mucosal microbes and activation of tolerogenic cytokines in ruminant animals.
Hong Shen, Zhongyan Lu, Zhihui Xu, Zanming Shen   +3 more
doaj   +1 more source

cDNA Cloning and Expression Analysis of Pattern Recognition Proteins from the Chinese Oak Silkmoth, Antheraea pernyi

Insects, 2012
Pattern recognition receptors play an important role in insect immune defense. We cloned the β-1,3-glucan recognition protein, lectin-5 and C-type lectin 1 genes of Antheraea pernyi and examined the expression profiles of immune-stimulated pupae.
Wenli Li, Suyun Fang, Yuan Li, Fengjuan Li, Olle Terenius   +4 more
doaj   +1 more source

Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis

Science, 2012
The Mycobiome In the past few years, much attention has been given to the trillions of bacterial inhabitants in our guts and the myriad of ways in which they influence our overall health. But what about fungi? Iliev et al. (p.
I. Iliev, Vincent A. Funari, K. Taylor, Quoclinh Nguyen, C. Reyes, Samuel P. Strom, Jordan Brown, Courtney A. Becker, P. Fleshner, M. Dubinsky, Jerome I. Rotter, Hanlin L. Wang, D. McGovern, Gordon D. Brown, D. Underhill   +14 more
semanticscholar   +1 more source

Helicobacter pylori metabolites exacerbate gastritis through C-type lectin receptors

Journal of Experimental Medicine, 2020
Helicobacter pylori is a pathogenic bacterium causing gastritis and malignancy; however, the underlying mechanism is not fully understood. Nagata et al. purify and identify virulent metabolites of H.
M. Nagata, K. Toyonaga, E. Ishikawa, Shojiro Haji, Nobuyuki Okahashi, Masatomo Takahashi, Yoshihiro Izumi, A. Imamura, Koichi Takato, H. Ishida, S. Nagai, P. Illarionov, B. L. Stocker, Mattie S. M. Timmer, D. G. Smith, Spencer J. Williams, T. Bamba, T. Miyamoto, M. Arita, B. Appelmelk, S. Yamasaki   +20 more
semanticscholar   +1 more source