Results 51 to 60 of about 239,318 (305)

C-type lectins facilitate tumor metastasis

Oncology Letters, 2016
Metastasis, a life-threatening complication of cancer, leads to the majority of cases of cancer-associated mortality. Unfortunately, the underlying molecular and cellular mechanisms of cancer metastasis remain to be fully elucidated. C-type lectins are a large group of proteins, which share structurally homologous carbohydrate-recognition domains (CRDs)
Ding, Dongbing, Yao, Yao, Zhang, Songbai, Su, Chunjie, Zhang, Yonglian   +4 more
openaire   +3 more sources

High mannose-specific lectin Msl mediates key interactions of the vaginal Lactobacillus plantarum isolate CMPG5300 [PDF]

, 2016
To characterize the interaction potential of the human vaginal isolate Lactobacillus plantarum CMPG5300, its genome was mined for genes encoding lectin-like proteins.
Balzarini, Jan, Imholz, Nicole CE, Lebeer, Sarah, Liekens, Sandra, Malik, Shweta, Noppen, Sam, Petrova, Mariya I, Schols, Dominique, Van Damme, Els, Vanderleyden, Jos, Verhoeven, Tine LA   +10 more
core   +1 more source

De novo assembly of transcriptomes from a B73 maize line introgressed with a QTL for resistance to gray leaf spot disease reveals a candidate allele of a lectin receptor-like kinase [PDF]

, 2020
Gray leaf spot (GLS) disease in maize, caused by the fungus Cercospora zeina, is a threat to maize production globally. Understanding the molecular basis for quantitative resistance to GLS is therefore important for food security.
Berger, Dave K., Pierneef, Rian, Scheepers, Kevin Daniel, Sterck, Lieven, Swart, Velushka, Van de Peer, Yves, Welgemoed, Tanya   +6 more
core   +2 more sources

Differing Expression and Potential Immunological Role of C-Type Lectin Receptors of Two Different Chicken Breeds against Low Pathogenic H9N2 Avian Influenza Virus

Pathogens
Diverse immune responses in different chicken lines can result in varying clinical consequences following avian influenza virus (AIV) infection. We compared two widely used layer breeds, Lohmann Brown (LB) and Lohmann White (LW), to examine virus ...
Sungsu Youk, Dong-Hun Lee, Chang-Seon Song   +2 more
doaj   +1 more source

C-Type Lectin Receptors in Host Defense Against Bacterial Pathogens

Frontiers in Cellular and Infection Microbiology, 2020
Antigen-presenting cells (APCs) are present throughout the human body—in tissues, at barrier sites and in the circulation. They are critical for processing external signals to instruct both local and systemic responses toward immune tolerance or immune ...
Malgorzata E. Mnich, Malgorzata E. Mnich, Rob van Dalen, Nina M. van Sorge, Nina M. van Sorge   +4 more
doaj   +1 more source

Identification of the Plasticity-Relevant Fucose-α(1−2)-Galactose Proteome from the Mouse Olfactory Bulb [PDF]

, 2009
Fucose-α(1−2)-galactose [Fucα(1−2)Gal] sugars have been implicated in the molecular mechanisms that underlie neuronal development, learning, and memory. However, an understanding of their precise roles has been hampered by a lack of information regarding
Domino, Steven E., Ficarro, Scott B., Hsieh-Wilson, Linda C., Krishnamurthy, Chithra, Murrey, Heather E., Peters, Eric C.   +5 more
core   +4 more sources

Drosophila C-type lectins enhance cellular encapsulation [PDF]

Molecular Immunology, 2007
C-type lectins are calcium-dependent carbohydrate binding proteins, and animal C-type lectins participate in innate immunity and cell-cell interactions. In the fruit fly Drosophila melanogaster, more than 30 genes encode C-type lectin domains. However, functions of Drosophila C-type lectins in innate immunity are not well understood.
Jingqun, Ao, Erjun, Ling, Xiao-Qiang, Yu
openaire   +2 more sources

Overexpression of Nictaba-like lectin genes from glycine max confers tolerance towards Pseudomonas syringae infection, aphid infestation and salt stress in transgenic Arabidopsis plants [PDF]

, 2016
Plants have evolved a sophisticated immune system that allows them to recognize invading pathogens by specialized receptors. Carbohydrate-binding proteins or lectins are part of this immune system and especially the lectins that reside in the ...
Smagghe, Guy, Van Damme, Els, Van Holle, Sofie   +2 more
core   +3 more sources

Human Galectins Induce Conversion of Dermal Fibroblasts into Myofibroblasts and Production of Extracellular Matrix: Potential Application in Tissue Engineering and Wound Repair [PDF]

, 2011
Members of the galectin family of endogenous lectins are potent adhesion/growth-regulatory effectors. Their multi-functionality opens possibilities for their use in bioapplications. We studied whether human galectins induce the conversion of human dermal
André A., S., André K., S., Barbora Dvořánková, Bergmann J., M., Cheb Y.-Y., S.-J., Dam T.K., Demetter O., P., Dvoránková J., B., Engelhardt H.-J., R., Eva Sykova, Fischer H., C., Fritz A., P., Hans-Joachim Gabius, Herbert Kaltner, Hung C.W., Jana Uhrova, Jones D.L., Jones G.E., Jones G.E., Karel Smetana, Jr., Kim Y.-B., H.-W., Kojima S., S., Lacina H., L., Lacina J., L., Lataillade T., J.-J., Legendre N., H., Lensch A., M., Lu J., Z.-H., Lukas Lacina, Miller S.N., Nagy I., N., Nakachi Y., K., Nogales-Gonzalés A., A., O’Donoghue J., K., Pavol Szabo, Pei S., Z., Peter Gal, Sabine André, Sanchez-Ruderisch C., H., Sanchez-Ruderisch S., H., Sansone S., F., Seyrek H., K., Smetana B., K., Smetana L., K., Smetana Z., K., Tomas Zima, Uchida K., K., von Reitzenstein J., C.   +47 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source