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The multiple roles of C-type lectin receptors in cancer [PDF]
C-type lectin receptors are a family of immune response receptors that can bind with a broad repertoire of ligands. It can function as innative immune receptors to surveillance bacteria, fungi, and virus invasions.
Qiao Li
doaj +2 more sources
C-Type Lectin Receptors in Asthma [PDF]
Asthma is a heterogeneous disease that affects approximately 300 million people worldwide, largely in developed countries. The etiology of the disease is poorly understood, but is likely to involve specific innate and adaptive responses to inhaled ...
Sabelo Hadebe +5 more
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Orientia tsutsugamushi binds to multiple C-type lectin receptors [PDF]
Orientia tsutsugamushi, the agent of scrub typhus, is an obligate intracellular bacterium whose atypical cell wall lacks many classical pathogen-associated molecular patterns but is enriched in neutral glycans.
Véronique Hefter +5 more
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MCL (macrophage C-type lectin) and mincle (macrophage inducible C-type lectin) comprise part of an extensive repertoire of pattern recognition receptors with the ability to sense damage associated and pathogen associated molecular patterns.
Mark B Richardson, Spencer J Williams
doaj +3 more sources
Targeting C-type Lectin Receptors for Cancer Immunity [PDF]
C-type lectin receptors (CLRs) are a large family of soluble and trans-membrane pattern recognition receptors that are widely and primarily expressed on myeloid cells.
Huimin eYan +6 more
doaj +3 more sources
The C‐type lectin‐like domain superfamily
The superfamily of proteins containing C‐type lectin‐like domains (CTLDs) is a large group of extracellular Metazoan proteins with diverse functions. The CTLD structure has a characteristic double‐loop (‘loop‐in‐a‐loop’) stabilized by two highly conserved disulfide bridges located at the bases of the loops, as well as a set of conserved hydrophobic and
Zelensky, Alex, Gready, Jill
openaire +5 more sources
C-type lectin-like receptor 2: roles and drug target [PDF]
C-type lectin-like receptor-2 (CLEC-2) is a member of the C-type lectin superfamily of cell surface receptors. The first confirmed endogenous and exogenous ligands of CLEC-2 are podoplanin and rhodocytin, respectively.
Lan Sun +5 more
doaj +2 more sources
The distribution of lectins across the phylum Nematoda : a genome-wide search [PDF]
Nematodes are a very diverse phylum that has adapted to nearly every ecosystem. They have developed specialized lifestyles, dividing the phylum into free-living, animal, and plant parasitic species. Their sheer abundance in numbers and presence in nearly
Bauters, Lander +2 more
core +6 more sources
Lectin ligands: New insights into their conformations and their dynamic behavior and the discovery of conformer selection by lectins [PDF]
The mysteries of the functions of complex glycoconjugates have enthralled scientists over decades. Theoretical considerations have ascribed an enormous capacity to store information to oligosaccharides, In the interplay with lectins sugar-code words of ...
Bovin, N. V. +11 more
core +16 more sources
Can Plant Lectins Help to Elucidate Insect Lectin-Mediated Immune Response?
Lectins are carbohydrate-binding proteins that recognize and selectively bind to specific sugar structures. This group of proteins is widespread in plants, animals, and microorganisms, and exerts a broad range of functions.
Pengyu Chen +3 more
doaj +1 more source

