Results 31 to 40 of about 5,064,919 (256)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Field Gladiolus (Gladiolus italicus Mill.): Contaminant of grain storage facilities [PDF]
Ratarstvo i PovrtarstvoArchaeological excavations in southeastern Serbia have unearthed previously undocumented charred seeds from the early to late antiquity. These seeds exhibit a semispherical, laterally compressed, and angular morphology.
Medović Aleksandar, Reuter Anna E.
doaj +1 more source
Plant macro remains of selected lakes in the Upper Lough Erne system
, 2019 Plant macro remains obtained in cores ULET2 (Upper Lough Erne), NCAS3 (Castle Lough), CBRAS1 (Cornabrass Lough), KILL2 (killymackan Lough) , GOLE1 (Gole Lough) and HEAD1 (Lough Head).
Sayer, Carl +19 more
core +1 more source
, 2021 Macro Supreme Anyway, the more lengthy out halting, the basically more plausible this shocking deal could sneak past, or supplies could get difficult to reach. flourishing enhancement for basically any take to have the option to get the past cutting edge
Macro Supreme
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Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
FEBS Open Bio, EarlyView.Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page +4 more
wiley +1 more source
Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
The rhizosphere microbiome and plant health [PDF]
, 2012 The diversity of microbes associated with plant roots is enormous, in the order of tens of thousands of species. This complex plant-associated microbial community, also referred to as the second genome of the plant, is crucial for plant health.
Pieterse, C.M.J. +4 more
core +2 more sources
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source