Results 41 to 50 of about 533,838 (264)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Konut ve Site Alanlarında Uygulanan Peyzaj Tasarımlarının Yeterliliği Üzerine Bir Araştırma: Tekirdağ Kenti

Düzce University Faculty of Forestry Journal of Forestry, 2016
Yaşadığımız kentlerde, sağlıksız büyümenin getirdiği sorunlara çözüm arayışı, bireylerin ve toplumun gereksinimlerinin nasıl karşılanacağı, kentlerin temel sorunlarının kaynağını oluşturmaktadır.
Murat Özyavuz, Yasin Dönmez
doaj  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Modified grape composition under climate change conditions requires adaptations in the vineyard

OENO One, 2017
Aim: Major effects of climate change are an increase in temperature, a modification in rainfall patterns and an increase in incoming radiations, in particular UV-Bs. Grapevines are highly sensitive to climatic conditions.
Cornelis van Leeuwen, Agnès Destrac-Irvine   +1 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Kent Ekolojisi Açısından Diyarbakır Kenti Açık-Yeşil Alanlarında Kullanılan Bitki Materyallerinin Değerlendirilmesi

Research in Agricultural Sciences
Kentsel açık yeşil alanlar, kentlerdeki bahçeler, parklar, yeşil koridorlar, yol peyzajı ve benzeri alanları kapsamaktadır. Bu alanlar rekreasyonel aktiviteler dışında insan psikoloji ve insanlar arası sosyal etkileşimi sağlayan önemli mekânlardır ...
Medine Çelik, Hasan Yılmaz
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Effect of fertilization and size of the corm on the multiplication of bananito seed (Musa AA)

Temas Agrarios, 2019
Baby Banana is preferred in national and international scenarios; however, availability and access to quality seed is limited. One mechanism to increase clonal supply is through plant material multiplication in thermal chambers.
Andrés Alfonso Patiño-Martínez, Gustavo Adolfo Rodriguez-Yzquierdo, Tatiana Camila Miranda-Salas, Luz Marina Lemus-Lemus   +3 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source