Results 81 to 90 of about 682,902 (306)
Integrated nutrient management, soil fertility, and sustainable agriculture [PDF]
The challenge for agriculture over the coming decades will be to meet the world's increasing demand for food in a sustainable way. Declining soil fertility and mismanagement of plant nutrients have made this task more difficult.
Goletti, Francesco +2 more
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Integrated nutrient management, soil fertility, and sustainable agriculture: current issues and future challenges [PDF]
The challenge for agriculture over the coming decades will be to meet the world's increasing demand for food in a sustainable way. Declining soil fertility and mismanagement of plant nutrients have made this task more difficult.
Goletti, Francesco +2 more
core
Nutritional and Defensive Chemistry of Three North American Ash Species: Possible Roles in Host Performance and Preference by Emerald Ash Borer Adults [PDF]
, 2018 Black ash (Fraxinus nigra), green ash (F. pennsylvanica), and white ash (F. americana) are the three most abundant ash species in the northeastern USA.
Chen, Yigen, Poland, Therese M
core +3 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
DEMAND FOR PLANT NUTRIENTS IN TENNESSEE DISAGGREGATED BY MIXED FERTILIZERS AND DIRECT APPLICATION MATERIALS [PDF]
When obtaining nitrogen (N), phosphate (P) and potash (K), purchasing decisions concerning the quantity and the form of each plant nutrient must be made.
Garrod, Peter V., Roberts, Roland K.
core +1 more source
AgronomyIn this study, the changes in yield, nutrient content, and amino acid levels in legume–cereal grass mixtures were qualitatively evaluated depending on the legume–cereal combination and inoculation with preparations based on Rhizobium.
Marden Baidalin +4 more
doaj +1 more source
Potassium: A Vital Regulator of Plant Responses and Tolerance to Abiotic Stresses
Agronomy, 2018 Among the plant nutrients, potassium (K) is one of the vital elements required for plant growth and physiology. Potassium is not only a constituent of the plant structure but it also has a regulatory function in several biochemical processes related to ...
Mirza Hasanuzzaman +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source