Results 101 to 110 of about 208,450 (303)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Nutrition strategies for obesity management
Background Obesity is a chronic disease that necessitates nutritional strategy for effective weight management. Behavioural modification relating to nutrients intake, food selection and dietary patterns are essential for sustaining long-term ...
Andayani, Diyah Eka +3 more
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Nutrition and production of Helianthus annuus in a function of application of leaf silicon
, 2019 Silicon (Si) is important as it increases plant tolerance to abiotic stresses. However, studies on in foliar fertilization are still scarce. The objective of this research was to evaluate the effect of foliar application of silicon on nutrition and ...
Flores, Rilner Alves +9 more
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Innovative Technologies in Plant Protection and Nutrition: Current Status and Global Trends
Technologie et InnovationPlants in the environment face constant stresses, either biotic or abiotic. These stresses can significantly reduce the productivity of important crops worldwide, with annual crop yield losses ranging from 25% to 50% of the total production.
George Daskas, Georgia Ouzounidou
doaj +1 more source
Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2011 The aim of this study was to examine the effects of the soil application of humus substances on the dry weight and the nutrient uptake of selected elements in maize grown under salt stress in greenhouse conditions.
Murat A. TURAN +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Memorandum and Letter from TAC Subcommittee on Plant Nutrition Chairman Vernon W. Ruttan
, 1974 3 October 1974 memorandum from TAC Subcommittee on Plant Nutrition chairman Vernon W. Ruttan to members of the subcommittee reporting the results of the subcommittee's 28 September 1974 meeting in Frankfurt.
CGIAR Technical Advisory Committee Subcommittee on Plant Nutrition +1 more
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FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source