Results 51 to 60 of about 201,044 (266)

The secretome of the environmental bacterium Pseudomonas protegens PBL3 has broad-spectrum antimicrobial activity against plant and human pathogenic bacteria

Microbiology Spectrum
Antimicrobials are widely used to manage bacterial diseases in humans, pets, and livestock. Unfortunately, their extensive use has contributed to the emergence of antimicrobial resistance (AMR), a threat to global health.
Biwesh Ojha, Kiyara Grosz, Clemencia M. Rojas   +2 more
doaj   +1 more source

A Covert Operation by a Plant Pathogen [PDF]

Cell Host & Microbe, 2016
Phytopathogens have mastered the ability to evade plant innate immunity. In this issue of Cell Host & Microbe, Zhou and colleagues (Li et al., 2016) uncover a strategy whereby a bacterial pathogen disables the plant immune system with such precision as to avoid triggering alarms that could potentially reveal its presence.
Jeff H, Chang, Javier F, Tabima
openaire   +2 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

A comprehensive catalogue of receptor-binding domains in extracellular contractile injection systems

Nature Communications
Extracellular contractile injection systems (eCISs) are bacteriophage tail-derived toxin delivery complexes in prokaryotes. They play roles in microbial interactions with hosts, using tail fiber proteins for target cell binding.
Nimrod Nachmias, Zhiren Wang, Xiao Feng, Feng Jiang, Asaf Levy   +4 more
doaj   +1 more source

Comparative genomics of Pseudomonas syringae pathovar tomato reveals novel chemotaxis pathways associated with motility and plant pathogenicity [PDF]

PeerJ, 2016
The majority of bacterial foliar plant pathogens must invade the apoplast of host plants through points of ingress, such as stomata or wounds, to replicate to high population density and cause disease.
Christopher R. Clarke, Byron W. Hayes, Brendan J. Runde, Eric Markel, Bryan M. Swingle, Boris A. Vinatzer   +5 more
doaj   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Physiological and genetic characterization of calcium phosphate precipitation by Pseudomonas species

Scientific Reports, 2018
Microbial biomineralization is a widespread phenomenon. The ability to induce calcium precipitation around bacterial cells has been reported in several Pseudomonas species but has not been thoroughly tested. We assayed 14 Pseudomonas strains representing
Maxwell R. Fishman, Krista Giglio, David Fay, Melanie J. Filiatrault   +3 more
doaj   +1 more source