Results 131 to 140 of about 141,193 (299)
, 1942 Alumni news magazine of the University of Minnesota Department of Plant Pathology.University of Minnesota: Department of Plant Pathology. (1942). Aurora Sporealis Vol.18(1).
University of Minnesota: Department of Plant Pathology
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
, 1927 Alumni news magazine of the University of Minnesota Department of Plant Pathology.University of Minnesota: Department of Plant Pathology. (1927). Aurora Sporealis Vol.03(1).
University of Minnesota: Department of Plant Pathology
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
, 1927 Alumni news magazine of the University of Minnesota Department of Plant Pathology.University of Minnesota: Department of Plant Pathology. (1927). Aurora Sporealis Vol.03(2).
University of Minnesota: Department of Plant Pathology
core
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
, 1945 Alumni news magazine of the University of Minnesota Department of Plant Pathology.University of Minnesota: Department of Plant Pathology. (1945). Aurora Sporealis Vol.21(3).
University of Minnesota: Department of Plant Pathology
core
The Plant Pathology Challenge 2020 data set to classify foliar disease of apples. [PDF]
Appl Plant Sci, 2020 Thapa R +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
, 1932 Alumni news magazine of the University of Minnesota Department of Plant Pathology.University of Minnesota: Department of Plant Pathology. (1932). Aurora Sporealis Vol.08(2).
University of Minnesota: Department of Plant Pathology
core