Results 111 to 120 of about 3,298,191 (304)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
, 1926 Alumni news magazine of the University of Minnesota Department of Plant Pathology.University of Minnesota: Department of Plant Pathology. (1926). Aurora Sporealis Vol.02(2).
University of Minnesota: Department of Plant Pathology
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Understanding the ramifications of quantitative ordinal scales on accuracy of estimates of disease severity and data analysis in plant pathology. [PDF]
Trop Plant Pathol, 2022 Chiang KS, Bock CH.
europepmc +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
, 1933 Alumni news magazine of the University of Minnesota Department of Plant Pathology.University of Minnesota: Department of Plant Pathology. (1933). Aurora Sporealis Vol.09(6).
University of Minnesota: Department of Plant Pathology
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
, 1998 Alumni news magazine of the University of Minnesota Department of Plant Pathology.University of Minnesota: Department of Plant Pathology. (1998). Aurora Sporealis Vol.68(1).
University of Minnesota: Department of Plant Pathology
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Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Aurora Sporealis Vol.26(4) - Vol.27(1)
, 1950 Alumni news magazine of the University of Minnesota Department of Plant Pathology.University of Minnesota: Department of Plant Pathology. (1950). Aurora Sporealis Vol.26(4) - Vol.27(1).
University of Minnesota: Department of Plant Pathology
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