Results 91 to 100 of about 141,193 (299)

Aurora Sporealis Vol.57(1)

open access: yes, 1987
Alumni news magazine of the University of Minnesota Department of Plant Pathology.University of Minnesota: Department of Plant Pathology. (1987). Aurora Sporealis Vol.57(1).
University of Minnesota: Department of Plant Pathology
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Aurora Sporealis 2017

open access: yes, 2017
News magazine of the University of Minnesota Department of Plant Pathology.University of Minnesota Department of Plant Pathology. (2017). Aurora Sporealis 2017.
University of Minnesota Department of Plant Pathology
core  

Plant Pathology and Public Health

open access: yesEmerging Infectious Diseases, 1999
Karen-Beth G. Scholthof
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Aurora Sporealis Vol.21(4)

open access: yes, 1945
Alumni news magazine of the University of Minnesota Department of Plant Pathology.University of Minnesota: Department of Plant Pathology. (1945). Aurora Sporealis Vol.21(4).
University of Minnesota: Department of Plant Pathology
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Aurora Sporealis Vol.27(4)

open access: yes, 1951
Alumni news magazine of the University of Minnesota Department of Plant Pathology.University of Minnesota: Department of Plant Pathology. (1951). Aurora Sporealis Vol.27(4).
University of Minnesota: Department of Plant Pathology
core  

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