Results 81 to 90 of about 141,193 (299)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Aurora Sporealis Vol.01(3)

open access: yes, 1925
Alumni news magazine of the University of Minnesota Department of Plant Pathology.University of Minnesota: Department of Plant Pathology. (1925). Aurora Sporealis Vol.01(3).
University of Minnesota: Department of Plant Pathology
core  

Selection and Experimental Evaluation of Universal Primers to Study the Fungal Microbiome of Higher Plants

open access: yesPhytobiomes Journal, 2019
The impact of primer choice on results of metabarcoding studies was experimentally evaluated by analyzing fungal communities associated with leaves of four plant species.
Silvia Scibetta   +4 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Aurora Sporealis Vol.13(2)

open access: yes, 1937
Alumni news magazine of the University of Minnesota Department of Plant Pathology.University of Minnesota: Department of Plant Pathology. (1937). Aurora Sporealis Vol.13(2).
University of Minnesota: Department of Plant Pathology
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Aurora Sporealis Vol.13(3)

open access: yes, 1937
Alumni news magazine of the University of Minnesota Department of Plant Pathology.University of Minnesota: Department of Plant Pathology. (1937). Aurora Sporealis Vol.13(3).
University of Minnesota: Department of Plant Pathology
core  

Digital plant pathology: a foundation and guide to modern agriculture. [PDF]

open access: yesJ Plant Dis Prot (2006), 2022
Kuska MT   +5 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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