Results 61 to 70 of about 141,193 (299)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Aurora Sporealis Vol.72(1)

, 2002
Alumni news magazine of the University of Minnesota Department of Plant Pathology. Incorrectly labeled as Vol. 71 (1) in print.University of Minnesota: Department of Plant Pathology. (2002). Aurora Sporealis Vol.72(1).
University of Minnesota: Department of Plant Pathology
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Aurora Sporealis Vol.28(3)

, 1952
Alumni news magazine of the University of Minnesota Department of Plant Pathology. Original publication incorrectly labeled as Volume 2.University of Minnesota: Department of Plant Pathology. (1952). Aurora Sporealis Vol.28(3).
University of Minnesota: Department of Plant Pathology
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A gene with a thousand alleles: The hyper-variable effectors of plant-parasitic nematodes

Cell Genomics
Summary: Pathogens are engaged in a fierce evolutionary arms race with their host. The genes at the forefront of the engagement between kingdoms are often part of diverse and highly mutable gene families. Even in this context, we discovered unprecedented
Unnati Sonawala, Helen Beasley, Peter Thorpe, Kyriakos Varypatakis, Beatrice Senatori, John T. Jones, Lida Derevnina, Sebastian Eves-van den Akker   +7 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Aurora Sporealis 2011

, 2012
The 2011 Aurora Sporealis covers news from the Department of Plant Pathology that occurred from 2010-2011. Its editor is Dean Malvick. The print and web edition are both 28 pages long.
University of Minnesota: Department of Plant Pathology
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Insights into the viral landscape of the western honey bee and native bees in Bangladesh

Microbiology Spectrum
Bees are important pollinators that are increasingly threatened by viruses. In this study, we investigated the viruses in honey bees in Bangladesh, focusing on western (Apis mellifera) and native bee species (A. cerana, A. dorsata, A. florea, and Trigona
Islam Hamim, Lena Wilfert
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Aurora Sporealis Vol.18(4)

, 1942
Alumni news magazine of the University of Minnesota Department of Plant Pathology.University of Minnesota: Department of Plant Pathology. (1942). Aurora Sporealis Vol.18(4).
University of Minnesota: Department of Plant Pathology
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