Results 51 to 60 of about 141,193 (299)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

A Phytophthora capsici virulence effector associates with NPR1 and suppresses plant immune responses

open access: yesPhytopathology Research, 2019
Salicylic acid (SA) plays a crucial regulatory role in plant immunity. NPR1 (non-expressor of pathogenesis related-1) is a SA receptor and plays a pivotal role in SA signaling.
Qi Li   +9 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Aurora Sporealis Vol.02(1)

open access: yes, 1926
Alumni news magazine of the University of Minnesota Department of Plant Pathology.University of Minnesota: Department of Plant Pathology. (1926). Aurora Sporealis Vol.02(1).
University of Minnesota: Department of Plant Pathology
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Polymorphism in natural alleles of the avirulence gene Avr1c is associated with the host adaptation of Phytophthora sojae

open access: yesPhytopathology Research, 2019
Phytophthora sojae is a destructive pathogen of soybean that is widely distributed in the world. The interaction between P. sojae and soybean follows the gene-for-gene model. The use of resistant soybean cultivars is the primary and most effective method
Jin Yang   +8 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Aurora Sporealis Vol.23(supplement)

open access: yes, 1947
Alumni news magazine of the Department of Plant Pathology.Chronicle of events of the first forty years of the Division of Plant Pathology and Botany at the University of Minnesota: 1907-1947.University of Minnesota: Department of Plant Pathology. (1947).
University of Minnesota: Department of Plant Pathology
core  

Plant pathology in the Czech Republic

open access: yesPlant Protection Science, 2002
An outline of past achievements in plant pathology in the CR and main recent problems of Czech plant pathologists are given. A description of the present state in plant pathology in the CR is preceded by data on the structure of CR, on its agriculture ...
V. Kůdela
doaj   +1 more source

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