Results 111 to 120 of about 2,965,344 (240)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
4th International Plant Phenotyping Symposium
, 2016 International Plant Phenotyping Symposium. El Batán, Texoco, México.
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Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Phenotyping and beyond: modelling the relationships between traits
, 2014 International audiencePlant phenotyping technology has become more advanced with the capacity to measure many morphological and physiological traits on a given individual.
Vile, Denis, Granier, Christine, C.
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Majlesi Journal of Electrical EngineeringPlant phenotyping is one of the recent research areas that play an essential role to develop a better understanding of plant traits, genotypes, stresses, and other related features.
Rama devi Kalluri, Prabha Selvaraj
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
, 2015 DPPN peruses a quantitative assessment of structural and functional relations of plants under various environmental conditions by establishing phenotyping infrastructure and the scientific basis for the innovative methods that are developed at the three ...
Altmann, Thomas +8 more
core
Minimum Information About Plant Phenotyping Experiments
, 2016 <p>Initial version of the MIAPPE (www.miappe.org) plant phenotyping data standard.</p ...
Pommier, Cyril
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source