Results 121 to 130 of about 2,516,713 (283)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Plant phenotyping and phenomics for plant breeding

open access: yes, 2017
A major challenge for food production in the coming decades is to meet the food demands of a growing population (Beddington, 2010). The difficulty of expanding agricultural land, along with the effect of climate change and the increase in world population are the current societal changes that make necessary to accelerate research to improve yield ...
Lobos, Gustavo A.   +5 more
openaire   +1 more source

A Review on Application of Various Deep Learning Techniques and Filtering Approach in Plant Phenotyping

open access: yesMajlesi Journal of Electrical Engineering
Plant phenotyping is one of the recent research areas that play an essential role to develop a better understanding of plant traits, genotypes, stresses, and other related features.
Rama devi Kalluri, Prabha Selvaraj
doaj   +1 more source

Phenotyping canopy-level photosynthetic responses to intermittent shading: beyond the daily light integral in multilayered cropping systems [PDF]

open access: yes
Multilayered cropping systems such as agrivoltaics, agroforestry, and intercropping create spatiotemporal light variability, including daily shade intermittence. While its physiological impacts are recognised, shade intermittence remains understudied and
Mc Cormick, Marcos   +7 more
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Exploring wheat genetic resources with shoot and root high-throughput phenotyping to improve adaptation to drought

open access: yes, 2018
Water availability is a major environmental stress threatening crops production worldwide, which impedes crop performance at all growth stages. Among a wide range of traits linked to drought resistance the root system plays an essential role in ensuring ...
PIGNONE D   +9 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Plant Phenotyping

open access: yesShokubutsu Kankyo Kogaku, 2023
openaire   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

GallOnt: An ontology for plant gall phenotypes

open access: yesBiodiversity Data Journal
Galls are novel plant structures that develop in response to select biotic stressors. These structures, extended phenotypes of the inducer, usually serve to protect and feed the inducer or its progeny. This life history strategy has evolved dozens of times, and tens of thousands of species—including many bacteria, fungi, nematodes, mites, and insects ...
Andrew Deans   +2 more
openaire   +3 more sources

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