Results 121 to 130 of about 2,516,713 (283)
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Plant phenotyping and phenomics for plant breeding
A major challenge for food production in the coming decades is to meet the food demands of a growing population (Beddington, 2010). The difficulty of expanding agricultural land, along with the effect of climate change and the increase in world population are the current societal changes that make necessary to accelerate research to improve yield ...
Lobos, Gustavo A. +5 more
openaire +1 more source
Plant phenotyping is one of the recent research areas that play an essential role to develop a better understanding of plant traits, genotypes, stresses, and other related features.
Rama devi Kalluri, Prabha Selvaraj
doaj +1 more source
Phenotyping canopy-level photosynthetic responses to intermittent shading: beyond the daily light integral in multilayered cropping systems [PDF]
Multilayered cropping systems such as agrivoltaics, agroforestry, and intercropping create spatiotemporal light variability, including daily shade intermittence. While its physiological impacts are recognised, shade intermittence remains understudied and
Mc Cormick, Marcos +7 more
core
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Water availability is a major environmental stress threatening crops production worldwide, which impedes crop performance at all growth stages. Among a wide range of traits linked to drought resistance the root system plays an essential role in ensuring ...
PIGNONE D +9 more
core
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
GallOnt: An ontology for plant gall phenotypes
Galls are novel plant structures that develop in response to select biotic stressors. These structures, extended phenotypes of the inducer, usually serve to protect and feed the inducer or its progeny. This life history strategy has evolved dozens of times, and tens of thousands of species—including many bacteria, fungi, nematodes, mites, and insects ...
Andrew Deans +2 more
openaire +3 more sources

