Results 101 to 110 of about 1,383,408 (312)

The ATPase hCINAP regulates 18S rRNA processing and is essential for embryogenesis and tumour growth

open access: yesNature Communications, 2016
Perturbations in ribosome biogenesis affect development and increase cancer susceptibility. Here, the authors show that hCINAP is required for 18S rRNA processing, is highly expressed in cancers, and promotes cancer cell growth by upregulating the ...
Dongmei Bai   +10 more
doaj   +1 more source

Metazoan tsRNAs: Biogenesis, Evolution and Regulatory Functions

open access: yesNon-Coding RNA, 2019
Transfer RNA-derived small RNAs (tsRNAs) are an emerging class of regulatory non-coding RNAs that play important roles in post-transcriptional regulation across a variety of biological processes.
Shengqian Dou, Yirong Wang, Jian Lu
doaj   +1 more source

Symposia on Plant (Protein) Phosphorylation [PDF]

open access: yesFrontiers in Plant Science, 2012
From September 14-16, 2011 the twelfth symposium on Plant Protein Phosphorylation was held in Tübingen, Germany. The topic is as broad as the name suggests and covers all aspects of this important means of protein modification in plants. I have had the pleasure of attending the 2007 and the 2011 symposia.
openaire   +4 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Viral-inducible Argonaute18 confers broad-spectrum virus resistance in rice by sequestering a host microRNA

open access: yeseLife, 2015
Viral pathogens are a major threat to rice production worldwide. Although RNA interference (RNAi) is known to mediate antiviral immunity in plant and animal models, the mechanism of antiviral RNAi in rice and other economically important crops is poorly ...
Jianguo Wu   +17 more
doaj   +1 more source

From A. rhizogenes RolD to Plant P5CS: Exploiting Proline to Control Plant Development [PDF]

open access: yes, 2018
The capability of the soil bacterium Agrobacterium rhizogenes to reprogram plant development and induce adventitious hairy roots relies on the expression of a few root-inducing genes (rol A, B, C and D), which can be transferred from large virulence ...
Costantino, Paolo   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Human activities reshape the spatial overlap between North Chinese leopard and its wild ungulate prey

open access: yesFrontiers in Zoology
Background Rapidly expanding human activities have profoundly changed the habitat use of both large carnivores and their prey, but whether and how human activities affect the interactions between them has received relatively less attention. In this study,
Yidan Wang   +3 more
doaj   +1 more source

Yersinia ruckeri challenge on rainbow trout fed different diet types [PDF]

open access: yes, 2010
A challenge for sustainable rainbow trout production is an increasing use of plant sources in fish feed due to shortage of marine protein and oil sources. Diets with high plant content are known to cause enteritis and injury to the intestine, which will
Dalsgaard, Inger, Madsen, Lone
core  

Virus-induced gene complementation reveals a transcription factor network in modulation of tomato fruit ripening [PDF]

open access: yes, 2012
Plant virus technology, in particular virus-induced gene silencing, is a widely used reverse- and forward-genetics tool in plant functional genomics. However the potential of virus technology to express genes to induce phenotypes or to complement mutants
Fan, Zaifeng   +15 more
core   +3 more sources

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