Results 31 to 40 of about 77,782 (292)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Plant regeneration from hypocotyl protoplasts of winter oilseed rape (Brassica napus L.)
Acta Societatis Botanicorum Poloniae, 2014 Protoplasts were isolated from hypocotyls of six breeding lines and two cultivars of winter oilseed rape (B. napus L.). Under presented culture conditions almost all of the protoplasts regenerated cell walls.
Wacław Orczyk, Anna Nadolska-Orczyk
doaj +1 more source
Recent Progress in Genetic Transformation and Gene Editing Technology in Cucurbit Crops
Agronomy, 2023 Cucurbits (Cucurbitaceae) include major horticultural crops with high nutritional and economic value that also serve as model plants for studying plant development and crop improvement.
Jing Feng +6 more
doaj +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Shoot induction and plant regeneration from cotyledon segments of the muskmelon variety "hógolyó"
International Journal of Horticultural Science, 1999 Cotyledonary segments of the casaba type muskmelon variety "Hógolyó" were used to induce organogenesis. Fifty different hormone combinations were applied to enhance the induction of shoot formation on the edge of the segments. The phases of organogenesis
Cs. Bársony +3 more
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Progress on medicinal plant regeneration and the road ahead
Medicinal Plant BiologyMedicinal plants, which are valuable to human beings, play indispensable roles in various fields, such as health care, health promotion, and quality of life enhancement.
Juan Wang +7 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
AGROBACTERIUM-MEDIATED TRANSFORMATION OF WHEAT [PDF]
Poljoprivreda, 2008 Transformation of cereals is one of the emerging areas for plant genomic and biotechnology research. Wheat was among the last major crops to be transformed by particle bombardment about 10 years ago.
K. Mészáros +4 more
doaj
In vitro morphogenic events in culture of Lotus corniculatus L. seedling root explants
Acta Societatis Botanicorum Poloniae, 2011 The experiments were carried out on Lotus corniculatus (L.) seedling root explants of the cultivar varieties Skrzeszowicka, Caroll A10 and strain 175.
Jan J. Rybczyński +4 more
doaj +1 more source