Results 61 to 70 of about 74,294 (347)
The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity
FEBS Open Bio, EarlyView.We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda +9 more
wiley +1 more source
Analytical methods applied to diverse types of Brazilian propolis
Chemistry Central Journal, 2011 Propolis is a bee product, composed mainly of plant resins and beeswax, therefore its chemical composition varies due to the geographic and plant origins of these resins, as well as the species of bee.
Marcucci Maria +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo +11 more
wiley +1 more source
Escalation of Plant Defense: Do Latex and Resin Canals Spur Plant Diversification?
The American Naturalist, 1991 Ehrlich and Raven's postulate that rapid diversification follows innovation in plant defense has often been invoked a posteriori for plant lineages of unusual diversity and chemical distinctiveness. The postulate can be more rigorously tested by defining a novel class of defense using chemical and/or anatomical criteria, independent of taxonomic ...
Farrell, Brian D. +2 more
openaire +3 more sources
FEBS Open Bio, EarlyView.In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li +5 more
wiley +1 more source
EXTRACTION AND SEPARATION OF SOME ACTIVE COMPOUNDS IN ERUCA SATIVA AND STIUDY IT'S BIOLOGICAL ACTIVITY [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2014 This study aimed to sperat and extract of some active compounds in Eruca sativa .It included identificaion and determination of active compounds their percentages in the leaves,stem and seeds,like(Tannine, Glycosides,Alkaloids,Saponins,Resins,Flavonoids ...
MOHAMMED HAMEED – AL MOHAMMDI +1 more
doaj +1 more source
Advanced Biology, EarlyView.The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran +5 more
wiley +1 more source
PLoS ONE, 2019 Honeybees (Apis mellifera) are threatened by numerous pathogens and parasites. To prevent infections they apply cooperative behavioral defenses, such as allo-grooming and hygiene, or they use antimicrobial plant resin.
Nora Drescher +3 more
doaj +1 more source
The Iraqi Journal of Veterinary Medicine, 2009 This study included evaluation of inhibition activity of watery and oily extracts of Rosmerinus officinalis plant on some pathogenic microorganisms like Salmonella typhi، Escheichia coli ، Staphylococcus aureus ، Klebsiella pneumoniae، Aeromonas ...
Auroba M.S. Ibrahim
doaj +1 more source
Synthesis and application of hypercrosslinked polymers with weak cation-exchange character for the selective extraction of basic pharmaceuticals from complex environmental water samples [PDF]
, 2010 The synthesis of high specific surface area sorbents (HXLPP-WCX) in the form of hypercrosslinked polymer microspheres with narrow particle size distributions, average particle diameters around 6 µm, and weak cation exchange (WCX) character, is described.
Borrull, F. +5 more
core +1 more source