Results 131 to 140 of about 7,938,123 (343)

Gip1 GPCR regulates two sexual-stage differentiation processes in the ascomycete Fusarium graminearum

open access: yesNature Communications
In ascomycetes, perithecium development involves sexual differentiation processes regulated by mating-related signaling pathways and mating-type locus (MAT) transcription factors, activated by uncharacterized receptors in response to stage-specific ...
Mingyu Ding   +10 more
doaj   +1 more source

Organisation, sequence diversity and evolution of a disease-resistance gene cluster in coffee tree (Coffea l.) [PDF]

open access: yes, 2008
Pathogen resistance (R) genes of the NBS-LRR class (for nucleotide binding site and leucine-rich repeat) are found in all plant species and confer resistance to a diverse spectrum of pathogens.
Combes, Marie-Christine   +4 more
core  

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

AcNAC10, regulated by AcTGA07, enhances kiwifruit resistance to Pseudomonas syringae pv. actinidiae via inhibiting jasmonic acid pathway

open access: yesMolecular Horticulture
Kiwifruit bacterial canker is a devastating disease caused by Pseudomonas syringae pv. actinidiae (Psa). NAC transcription factors play a significant role in host immunity.
Chao Zhao   +8 more
doaj   +1 more source

Mapping of quantitative adult plant field resistance to leaf rust and stripe rust in two European winter wheat populations reveals co-location of three QTL conferring resistance to both rust pathogens [PDF]

open access: hybrid, 2014
Maria Buerstmayr   +9 more
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

High‐throughput in planta expression screening identifies a class II ethylene‐responsive element binding factor‐like protein that regulates plant cell death and non‐host resistance [PDF]

open access: bronze, 2005
Khairun Nasir   +12 more
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Agronomic performance of 27 cocoa progenies and plant selection based on productivity, self-compatibility and disease resistance [PDF]

open access: gold, 2013
Milton Macoto Yamada   +4 more
openalex   +1 more source

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