Results 211 to 220 of about 1,346,458 (344)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Plant-aphid interactions: recent trends in plant resistance to aphids. [PDF]

open access: yesStress Biol
Gebretsadik KG   +12 more
europepmc   +1 more source

Soybean microbiome composition and the impact of host plant resistance. [PDF]

open access: yesFront Plant Sci, 2023
Tran DT   +4 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Glycosylation of N-hydroxy-pipecolic acid equilibrates between systemic acquired resistance response and plant growth [PDF]

open access: bronze, 2020
Jianghua Cai   +6 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Dissecting adult plant resistance to stem rust through multi-model GWAS in a diverse barley germplasm panel. [PDF]

open access: yesFront Plant Sci
Genievskaya Y   +6 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy