Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
A large-scale multi-environment study dissecting adult-plant resistance haplotypes for stripe rust resistance in Australian wheat breeding populations. [PDF]
Vo Van-Zivkovic N +7 more
europepmc +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
Adult-plant resistance to leaf scald and net form net blotch in food barley genotypes at a hot spot location in Ethiopia. [PDF]
Ababa G +4 more
europepmc +1 more source
Genome-Wide Identification of the Sulfate Transporter Gene Family Reveals That <i>BolSULTR2;1</i> Regulates Plant Resistance to <i>Alternaria brassicicola</i> Through the Modulation of Glutathione Biosynthesis in Broccoli. [PDF]
Wu G, Ding Y, Li N, Zhang H, Liu N.
europepmc +1 more source
Morinda citrifolia Essential Oil: A Plant Resistance Biostimulant and a Sustainable Alternative for Controlling Phytopathogens and Insect Pests. [PDF]
Dias BL +14 more
europepmc +1 more source
Resistance to fungicides in the plant pathogen Microdochium nivale
Ryan Gourlie
openalex +1 more source

