Results 81 to 90 of about 380,324 (308)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Special Issue “Basic and Applied Sciences for Intelligent Plant Production Systems”

Environment Control in Biology, 2009
The Japanese Society of Agricultural, Biological and Environmental Engineers and Scientists held an international symposium titled “Basic and Applied Sciences for Intelligent Plant Production Systems” on the 9th of September 2008, Ehime University, Matsuyama, Japan. From that symposium, this special issue for “Basic and Applied Sciences for Intelligent
openaire   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Exploring plant growth promoting traits and biocontrol potential of new isolated Bacillus subtilis BS-2301 strain in suppressing Sclerotinia sclerotiorum through various mechanisms

Frontiers in Plant Science
Sclerotinia sclerotiorum (Lib.) de Bary is the causative agent of stem white mold disease which severely reduces major crop productivity including soybean and rapeseed worldwide.
Muhammad Ayaz, Muhammad Ayaz, Qurban Ali, Wei Zhao, Yuan-Kai Chi, Farman Ali, Khan Abdur Rashid, Shun Cao, Yan-qiu He, Abdul Aziz Bukero, Wen-Kun Huang, Ren-De Qi   +11 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Differential gene expression in nearly isogenic lines with QTL for partial resistance to Puccinia hordei in barley [PDF]

, 2010
Background The barley-Puccinia hordei (barley leaf rust) pathosystem is a model for investigating partial disease resistance in crop plants and genetic mapping of phenotypic resistance has identified several quantitative trait loci (QTL) for partial ...
Hedley Peter E, Vels, S.A., Thierry C Marcel, Chen, Xinwei, Chen, X., Rients E Niks, Niks, Rients, Hedley, Peter, Hedley, Peter E., Druka, Arnis, Hedley, P.E., Marcel, Thierry C., Marcel, Thierry, T., Vels, Anton, Peter E Hedley, Anton Vels, Druka Arnis, Marcel, T.C., Arnis Druka, Morris Jenny, Morris, J., Waugh, R., Marcel, Thierry, Xinwei Chen, Vels Anton, Niks, R.E., Robbie Waugh, Chen Xinwei, Druka, A., Waugh, Robbie, Waugh Robbie, Niks Rients E, Jenny Morris, Niks, Rients E., Marcel Thierry C, Waugh, Robbie; id_orcid, Morris, Jenny   +36 more
core   +1 more source

Plant-derived pharmaceuticals - the road forward

, 2022
S.580-585Plant-derived pharmaceuticals are poised to become the next major commercial development in biotechnology. The advantages they offer in terms of production scale and economy, product safety, ease of storage and distribution cannot be matched by ...
Ma, J.K.-C., Sparrow, P., Fischer, R., Twyman, R.M., Mahoney, R., Chikwamba, R.   +5 more
core   +1 more source

What does precision crop production hold for the future of soil science and plant nutrition?

Acta Agraria Debreceniensis, 2018
The concept of precision agriculture is straightforward at the scientific level but even basic goals are blurred at the level of everyday practice in the Hungarian crop production despite the fact that several elements of the new technology have already been applied. The industrial and the service sectors offer many products and services to the farmers
István Sisák, András Benő, Mihály Kocsis   +2 more
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source